Ann Dermatol.  2009 Aug;21(3):311-314. 10.5021/ad.2009.21.3.311.

A Case of Eczema Herpeticum with Hailey-Hailey Disease

  • 1Department of Dermatology, Soonchunhyang University College of Medicine, Seoul, Korea.


Eczema herpeticum is the dissemination of herpes simplex virus in the setting of a preexisting skin disease. Hailey- Hailey disease [familial benign chronic pemphigus] is a blistering dermatosis that is inherited as an autosomal dominant trait and it usually presents itself around the third or fourth decades. Coexistence of eczema herpeticum and Hailey-Hailey disease is an infrequent occurrence. Four such cases have been reported in the English and German medical literature. We report here on an unusual case of eczema herpeticum that coexisted with Hailey-Hailey disease in a 47 years old man and we review the relevant literatures.


Eczema herpeticum; Hailey-Hailey disease

MeSH Terms

Kaposi Varicelliform Eruption
Pemphigus, Benign Familial
Skin Diseases


  • Fig. 1 Multiple umbilicated vesicles on the chin.

  • Fig. 2 Erythematous scaly plaque with maceration of the inguinal area (A), the nape of the neck (B) and the axilla (C).

  • Fig. 3 Intraepidermal clefts suprabasally in the epidermis and the characteristic acantholysis with the appearance of a "dilapidated brick wall" (H&E stain, ×100).


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