Ann Dermatol.  1999 Oct;11(4):271-275. 10.5021/ad.1999.11.4.271.

Hailey-Hailey Disease with a Family Histroy and Unique Nail Lesions

• Jung MJ
• Lee SJ
• Cho YW
• Han JY
• Song KY

• KMID: 2383039
• DOI: http://doi.org/10.5021/ad.1999.11.4.271

Abstract

Hailey-Hailey disease(benign familial chronic pemphigus) is a rare autosomal dominant disorder characterized by blisters at sites of friction such as the neck, axillae and groin which are caused by suprabasal epidermal acantholysis. We report two cases of Hailey-Hailey disease in the one family. One of the two cases has asymptomatic multiple longitudinal white bands in the fingernails associated with typical skin lesions. The nail lesions have not been described until reported by Burge in 1992 and it may be a characteristic finding in Hailey-Hailey disease.

Keyword

Family history; Hailey-hailey disease; Unique nail lesions

MeSH Terms

Acantholysis
Axilla
Blister
Friction
Groin
Humans
Nails
Neck
Pemphigus, Benign Familial*
Skin