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Cold chain time- and temperature-controlled transport of vaccines: a simulated experimental study

Ng CZ, Lean YL, Yeoh SF, Lean QY, Lee KS, Suleiman A, Liew KB, Kassab YW, Al-Worafi , Ming LC

PURPOSE: The objective of this research was to examine the cold chain temperature maintenance for the supply of vaccines and other biological products by pharmaceutical wholesaler. MATERIALS AND METHODS: In this...
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Radiological Characteristics of Materials Used in 3-Dimensional Printing with Various Infill Densities

Park SY, Choi N, Choi BG, Lee DM, Jang NY

Radiological properties of newly introduced and existing 3-dimensional (3D) printing materials were evaluated by measuring their Hounsfield units (HUs) at varying infill densities. The six materials for 3D printing which...
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Pharmacologic Treatment of Chronic Hyperkalemia in Patients with Chronic Kidney Disease

Kim GH

Hyperkalemia is frequently complicated in patients with advanced chronic kidney disease (CKD) because kidney is the major route of potassium excretion. Urinary potassium excretion is reduced according to the decline...
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Influence of Cell Surface Hydrophobicity on Adhesion and Biofilm Formation in Candida albicans and Several Bacterial Species

Park SJ, Lee KH

The purpose of this study is to investigate the correlation of cell surface hydrophobicity (CSH) and biofilm formation or adhesion in Candida albicans (C. albicans) and several pathogenic bacteria. All...
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Adhesion and Biofilm Formation Abilities of Bacteria Isolated from Dental Unit Waterlines

Yoon HY, Lee SY

The purpose of our study is to compare the adhesion and biofilm formation abilities of isolates from water discharged from dental unit waterlines (DUWLs). Bacteria were isolated from a total...
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An in vitro model of Fusobacterium nucleatum and Porphyromonas gingivalis in single- and dual-species biofilms

Tavares LJ, Klein MI, Panariello BHD, Dorigatti de Avila E, Pavarina A

PURPOSE: The goal of this study was to develop and validate a standardized in vitro pathogenic biofilm attached onto saliva-coated surfaces. METHODS: Fusobacterium nucleatum (F. nucleatum) and Porphyromonas gingivalis (P. gingivalis)...
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Substrate roughness induces the development of defective E-cadherin junctions in human gingival keratinocytes

Jin C, Lee G, Oh C, Kim HJ, Kim HM

PURPOSE: The entry of bacteria or harmful substances through the epithelial seal of human gingival keratinocytes (HGKs) in the junctional epithelium (JE) is blocked by specialized intercellular junctions such as...
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Regeneration of Recurrent Laryngeal Nerve using Polycaprolactone (PCL) Nerve Guide Conduit Coated with Conductive Materials

Choi JS, Kim H, An HY, Shim BS, Lim JY

BACKGROUND AND OBJECTIVES: Recurrent laryngeal nerve (RLN) damage commonly occurs from a thyroid surgery and causes communication impairment, aspiration and dysphagia. The purpose of this study is to develop a...
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In vitro Comparison of Anti-Biofilm Effects against Carbapenem-Resistant Acinetobacter baumannii: Imipenem, Colistin, Tigecycline, Rifampicin and Combinations

Song JY, Cheong HJ, Noh JY, Kim WJ

BACKGROUND: Multi-drug resistant (MDR) Acinetobacter baumannii has emerged as one of the most important nosocomial pathogens. In addition to the diverse resistance mechanisms, some A. baumannii strains are known to...
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Synergistic effect of xylitol and ursolic acid combination on oral biofilms

Zou Y, Lee Y, Huh J, Park JW

OBJECTIVES: This study was designed to evaluate the synergistic antibacterial effect of xylitol and ursolic acid (UA) against oral biofilms in vitro. MATERIALS AND METHODS: S. mutans UA 159 (wild type),...
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Disseminated Neonatal Herpes Simplex Virus Infection

Lee B, Hwang J, Choi YH, Han YJ, Choi YH, Park JD

Disseminated neonatal herpes simplex virus (HSV) infection is one of the most severe neonatal infections, and can have devastating consequences without early proper treatment. However, the administration of acyclovir can...
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A case of familial X-linked thrombocytopenia with a novel WAS gene mutation

Lee EK, Eem YJ, Chung NG, Kim MS, Jeong DC

  • KMID: 2353173
  • Korean J Pediatr.
  • 2013 Jun;56(6):265-268.
Wiskott-Aldrich syndrome (WAS) is an inherited X-linked disorder. The WAS gene is located on the X chromosome and undergoes mutations, which affect various domains of the WAS protein, resulting in...
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Herpes Simplex Encephalitis Suffered Rotatory Dizziness as a Primary Symptom

Choi SA, Byun JY, Lee SK

  • KMID: 1426869
  • Res Vestib Sci.
  • 2013 Jun;12(2):67-71.
Herpes simplex encephalitis (HSE) is rare, serious sporadic encephalitis associated with high mortality in untreated cases. Although cognitive impairment with fever could be the clue of diagnosis, various symptoms can...
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Inhibition of Streptococcus mutans biofilm formation on composite resins containing ursolic acid

Kim S, Song M, Roh BD, Park SH, Park JW

OBJECTIVES: To evaluate the inhibitory effect of ursolic acid (UA)-containing composites on Streptococcus mutans (S. mutans) biofilm. MATERIALS AND METHODS: Composite resins with five different concentrations (0.04, 0.1, 0.2, 0.5, and...
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Upper Gastrointestinal Hemorrhage from Esophageal Ulcer Caused by Coinfection of Herpes Simplex Virus and Cytomegalovirus in Immunocompromised Patient

Chung HH, Jang JY, Byun JM, Park SH, Kim DH, Chang YW

Coinfection with herpes simplex virus and cytomegalovirus is a very rare cause of esophageal ulcer and upper gastrointestinal hemorrhage. A 26 year-old male kidney transplant recipient was referred with a...
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A Case of Epidermolysis Bullosa Simplex (Other Generalized Type)

Ko DY, Ha SM, Jeon SY, Kim DC, Song KH, Kim KH

  • KMID: 2247246
  • Korean J Dermatol.
  • 2013 Mar;51(3):219-222.
The other generalized type of epidermolysis bullosa simplex (EBS) is a genetic blistering skin disease, caused by a mutation of the genes encoding keratin 5 and 14. EBS starts at...
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Telemedicine of Skin Diseases in Ulleung Island

Kim SA, Cho JW, Lee KS

  • KMID: 2038545
  • Korean J Dermatol.
  • 2013 Jan;51(1):8-12.
BACKGROUND: Telemedicine can be useful in dermatology on Ulleung island which is 217 km away from Pohang and without dermatologists. OBJECTIVE: The purpose of this study is to measure the effectiveness...
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Anisakidosis in Korea; Changes Over the Last Decade

Cha HJ, Ock MS

Anisakidosis is caused by Anisakis simplex and other anisakids larvae parasitizing marine fish and cephalopods. A lot of case reports about anisakidosis have been published in Korea because of raw...
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Role of TGF-beta in Survival of Phagocytizing Microglia: Autocrine Suppression of TNF-alpha Production and Oxidative Stress

Ryu KY, Cho GS, Piao HZ, Kim WK

Microglia are recognized as residential macrophageal cells in the brain. Activated microglia play a critical role in removal of dead or damaged cells through phagocytosis activity. During phagocytosis, however, microglia...
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Glutamine and Leucine Provide Enhanced Protective Immunity Against Mucosal Infection with Herpes Simplex Virus Type 1

Uyangaa E, Lee HK, Eo SK

Besides their role as building blocks of protein, there are growing evidences that some amino acids have roles in regulating key metabolic pathways that are necessary for maintenance, growth, reproduction,...
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