Ann Dermatol.  2010 Aug;22(3):319-322. 10.5021/ad.2010.22.3.319.

A Case of Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum that Developed in a Nevus Sebaceus

• Kim MS
• Lee JH
• Lee WM
• Son SJ

• KMID: 2265367
• DOI: http://doi.org/10.5021/ad.2010.22.3.319

Abstract

Tubular apocrine adenoma (TAA) is a very rare sweat gland tumor. TAA and syringocystadenoma papilliferum (SCAP) rarely develop together in a nevus sebaceus (NS). Herein, we report on a 40-year-old Korean woman with TAA associated with SCAP that developed in a NS located on the scalp.

Keyword

Nevus sebaceus; Syringocystadenoma papilliferum; Tubular apocrine adenoma

MeSH Terms

Adenoma
Adult
Female
Humans
Nevus
Scalp
Sweat Glands

Figure

• 

  Fig. 1 A solitary, 2.5×2.5 cm well-circumscribed, erosive, erythematous lobulated nodule on the scalp.

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  Fig. 2 Syringocystadenoma papilliferum in the upper portion of the lesion and tubular apocrine adenoma in the lower portion (H&E, ×12.5).

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  Fig. 3 Findings of the upper part of the lesion. (A) Cystic and irregularly dilated tubular structures with deep invagination (H&E, ×200). (B) The lumina are lined by 2 layers of epithelial cells embedded in a fibroblastic stroma with a plentiful plasma cell infiltration (H&E, ×400).

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  Fig. 4 Findings of the lower part of the lesion. (A) Variable sized tubular structures are seen (H&E, ×100). (B) Two layers of cells with evidence of decapitation secretion of the luminal cells are seen (H&E, ×400).

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  Fig. 5 (A) Only focally positive staining results in the syringocystadenoma papilliferum (SCAP) lesion (GCDFP-15, ×100). (B) Strong positive staining results in the tubular apocrine adenoma (TAA) lesion (GCDFP-15, ×200).

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