Korean J Med.
2012 Mar;82(3):321-325.
A Case of Brunner's Gland Hyperplasia with Dysplasia
- Affiliations
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- 1Department of Internal Medicine, Good Gang-An Hospital, Busan, Korea. doongpa@gmail.com
Abstract
- Brunner's gland hyperplasia, also known as Brunner's gland adenoma, polypoid hamartoma, or Brunneroma, is a rare proliferative lesion arising from the Brunner's glands of the duodenum. These lesions have been described previously as benign, with no malignant potential. We report a case of Brunner's gland hyperplasia in the duodenum that was discovered incidentally during the endoscopic evaluation of anal bleeding. Histopathological examination of this Brunner's gland hyperplasia revealed well-marked, low-grade dysplasia. This case suggests a dysplastic stage with malignant potential in the natural history of Brunner's gland hyperplasia.