Korean J Gastrointest Endosc.  2009 Oct;39(4):236-239.

A Case of Cystic Brunner's Gland Hyperplasia with Intracystic Inverted Growth

• Hong SI
• Kim JI
• Lee HS
• Kim GM
• Park JM
• Cheung DY
• Park SH
• Kim JK

Abstract

Cystic Brunner's gland hyperplasia is a benign lesion of the duodenum that may not be familiar to gastroenterologists because of its rarity. Moreover, cystic Brunner's gland hyperplasia with intacystic inverted growth is more uncommon lesion. Here, we report a case of cystic Brunner's gland hyperplasia in a 34-year-old man. An endoscopy of the upper digestive tract revealed the presence of a 1.2 cm sized polypoid mass of the duodenal second portion. Endoscopic submucosal dissection was performed to remove the mass. Microscopically, a cystic lesion was seen in the submucosa underneath the normal surface duodenal mucosa. Hyperplastic Brunner's glands were seen close by the cyst. The cyst was lined by a layer of columnar epithelium similar to that of Brunner's gland ducts with no cytologic atypia. Also, a part of the cyst lining was inverted into the cyst lumen with fibrovascular core. Therefore, The final diagnosis was a cystic Brunner's gland hyperplasia with intracystic inverted growth.

Keyword

Brunner's gland hyperplasia; Cystic; Inverted

MeSH Terms

Adult
Brunner Glands
Duodenum
Endoscopy
Epithelium
Gastrointestinal Tract
Humans
Hyperplasia
Mucous Membrane