Korean J Obstet Gynecol.  2002 Apr;45(4):723-727.

A case of neonatal lupus syndrome with congenital complete heart block

• Chung SH
• Lee Y
• Cheon YH
• Jung IC
• Yoon WS
• Lee JS
• Yi CS
• Lee JK
• Kim SP

Abstract

The neonatal lupus syndrome is characterized by skin lesions, hepatic and hematologic abnormalities and congenital heart block. Congenital heart block which is believed to be caused by transplacental passage of the anti-Ro (SSA)/La (SSB) antibodies from mother to infant, is known to occur in 1 in 20,000 live births. In contrast to other manifestation of neonatal lupus syndrome, which usually subside within 6 months after birth, congenital heart block is a permanent and potentially fatal complication. We experienced a case of neonatal lupus syndorme with congenital complete heart block in a newborn of asyptomatic mother with anti-Ro (SSA)/ La (SSB) antibodies.

Keyword

neonatal lupus syndrome; congenital complete heart block; anti-Ro (SSA)/La (SSB) antibodies

MeSH Terms

Antibodies
Heart Block*
Heart*
Humans
Infant
Infant, Newborn
Live Birth
Mothers
Parturition
Skin
Antibodies