Korean J Intern Med.  2011 Jun;26(2):213-215. 10.3904/kjim.2011.26.2.213.

Complete Atrioventricular Block in Adult Sjogren's Syndrome with Anti-Ro Autoantibody

• Sung MJ
• Park SH
• Kim SK
• Lee YS
• Park CY
• Choe JY

• KMID: 1776596
• DOI: http://doi.org/10.3904/kjim.2011.26.2.213

Abstract

Anti-Ro autoantibody is associated with Sjogren's syndrome (SS), systemic lupus erythematosus (SLE), and neonatal lupus syndrome (i.e., congenital complete heart block in newborns). Generally, the adult atrioventricular (AV) node is believed to be relatively resistant to the scarring effects of anti-Ro/anti-La autoantibodies. However, there have been some reports of adult complete AV block in SS and SLE patients. Here, we report a case of complete heart block in primary SS with anti-Ro autoantibodies, with no other risk factor for the development of heart block, and review their etiological association.

Keyword

Ro antibodies; Sjogren's syndrome; Atrioventricular block

MeSH Terms

Antibodies, Antinuclear/*blood
Atrioventricular Block/diagnosis/*immunology/therapy
Cardiac Pacing, Artificial
Electrocardiography
Electrocardiography, Ambulatory
Exercise Test
Female
Humans
Middle Aged
Predictive Value of Tests
Risk Factors
Sjogren's Syndrome/complications/*immunology
Treatment Outcome