Ann Dermatol.  1998 Jul;10(3):185-189. 10.5021/ad.1998.10.3.185.

Neonatal Lupus Erythematosus

• Lee HP
• Lee HN
• Houh D
• Byun DG
• Baek SC

• KMID: 2359788
• DOI: http://doi.org/10.5021/ad.1998.10.3.185

Abstract

Neonatal lupus erytematosus is a distinct subset of lupus erythematosus. It is characterized by cutaneous findings exhibiting the morphology of subacute cutaneous lupus erythematosus, congenital heart block, and anti-Ro/SSA and/or anti-La/SSB autoantibodies which result from the transplacental passage of maternal autoantibodies. We report a case of a 12-week-old female infant who presented with characteristic clinical and histopathological features of cutaneous neonatal lupus erythematosus but without evidence of congenital heart block. Initial serological studies reveled the presence of anti-La/SSB anti-bodies and antinuclear antibodies. 5 months later, follow-up serology was negative in accordance with a clinical remission.

Keyword

Neonatal lupus erythematosus; Autoantibodies

MeSH Terms

Antibodies, Antinuclear
Autoantibodies
Female
Follow-Up Studies
Heart Block
Humans
Infant
Lupus Erythematosus, Cutaneous
Antibodies, Antinuclear
Autoantibodies