Korean J Obstet Gynecol.  2002 Mar;45(3):529-532.

A Case of Antenatally Detected Schizencephaly

Affiliations
  • 1Department of Obstetrics and Gynecology, Dong-Gang Hospital, Ulsan, Korea.
  • 2Department of Diagnostic Radiology, Dong-Gang Hospital, Ulsan, Korea.

Abstract

Schizencephaly is an unusual condition rarely detected antenatally. It is a neuronal migrational disorder consisting of clefts in the brain that communicate with the lateral ventricles. The etiology and the pathogenesis is not clearly estabilished. While some authors advocate a vascular insult with a secondary effect on brain development, others suggest a primary cerebral dysgenesis by genetic or acquired factors. The importance of making an accurate antenatal diagnosis is that the outcome for schizencephaly in considerably poor than for other causes of ventriculomegaly. Typical symtoms include seizures, mental retardation, spastic tetraplagia and blindness. We report a case of typeIIschizencephaly that was diagnosed antenatally in the third trimester with a brief reiew of literatures.

Keyword

Schizencephaly; Antenatal diagnosis

MeSH Terms

Blindness
Brain
Female
Humans
Intellectual Disability
Lateral Ventricles
Malformations of Cortical Development*
Muscle Spasticity
Neurons
Pregnancy
Pregnancy Trimester, Third
Prenatal Diagnosis
Seizures
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