Korean J Obstet Gynecol.  2002 Feb;45(2):327-331.

A Case of Uterine Rupture in Pregnancy Complicated with Myelodysplastic Syndrome

• Lim BD
• Lee HW
• Joo SH
• Jung ES
• Park CS
• Cho SJ

Abstract

Myelodysplastic syndrome (MDS) is a relatively uncommon hematological disorder, charactedzed by cytopenia in the peripheral blood and normo-or hypercellularity in the bone marrow with morphological dysplastic change. Ineffective hematopoiesis leads to hematological failures in this syndrome. MDS is largeIy affected in older individuaIs with a median age of 60-75. It's association with pregnancy is even rarer. Although the exact incidence of MDS in pregancy is unknown, it is likely to be less than 1 per 100,000 pregnancies annually. Recently, we experienced a case of MDS presented initially during pregnancy in a 34-year-old primipara and managed with intensive hematologic support. Uerine rupture occurred in pregnancy complicated with MDS at 34 gestation weeks and a healthy infant was successfully delivered by Cesarean section. We report this case with a brief review of the literature.

Keyword

Myelodysplastic syndrome; Pregnancy; Uterine rupture

MeSH Terms

Adult
Bone Marrow
Cesarean Section
Female
Hematopoiesis
Humans
Incidence
Infant
Myelodysplastic Syndromes*
Pregnancy*
Rupture
Uterine Rupture*