Korean J Obstet Gynecol.  2000 Jul;43(7):1269-1272.

A Case of Choriocarcinoma following Term Pregnancy

• Lee CB
• Jang YC
• Lee JH
• Lee JS
• Lee JY
• Lee SA
• Kim JW

Abstract

Gestational trophoblastic tumor became one of the curable disease due to the development of chemotherapy, appropriate follow up of beta- human chorionic gonadotropin and others. But metastatic trophoblastic tumor still shows high mortality rate because of resistance to the chemotherapy and large tumor burden.One of the important prognostic factors determining the prognosis of gestational trophoblastic tumor is antecedent pregnancy, which affects the response to therapy. Choriocarcinoma following term pregnancy is rare one with the incidence of one per 160,000 pregnancies in United States and the prognosis is poor because of late diagnosis and combined high risk prognostic factors.We present a choriocarcinoma following term pregnancy that required emergency total abdominal hysterectomy due to profuse bleeding with brief review of literatures.

Keyword

Choriocarcinoma; term pregnancy; profuse bleeding

MeSH Terms

Choriocarcinoma*
Chorionic Gonadotropin
Delayed Diagnosis
Drug Therapy
Emergencies
Female
Follow-Up Studies
Hemorrhage
Hysterectomy
Incidence
Mortality
Pregnancy
Pregnancy*
Prognosis
Trophoblastic Neoplasms
United States
Chorionic Gonadotropin