Korean J Gynecol Oncol Colposc.  2000 Sep;11(3):312-317.

A Case of Metastatic Choriocarcinoma with Uterine Perforation following Term Pregnancy

• Yang HJ
• Kim HO
• Han JE
• Chon SH

Abstract

Gestational trophoblastic tumor is one of the curable disease, but metastatic trophoblastic tumor still shows high mortality rate because of resistance to the chemotherapy. Choriocarcinoma may occur after an any type of human pregnancy. The incidence of choriocarcinoma following term pregnancy is very uncommon, and such tumor appears to follow a more aggressive course with more extensive metastatic spread and is less responsive to chemotherapy resulting in a poorer prognosis. Choriocarcinoma presenting as postpartum hemorrhage, and spontaneous tumor perforation with intra-abdominal hemorrhage is even rarer, requiring emergency laparotomy. We had experienced one case of metastatic choriocarcinoma following term pregnancy that required emergency total abdominal hysterectomy due to uterine perforation and hemorrhage. So, we report this case with brief review of literatures.

Keyword

Choriocarinoma; Uterine perforation; Postpartum bleeding

MeSH Terms

Choriocarcinoma*
Drug Therapy
Emergencies
Female
Hemorrhage
Humans
Hysterectomy
Incidence
Laparotomy
Mortality
Postpartum Hemorrhage
Pregnancy
Pregnancy*
Prognosis
Trophoblastic Neoplasms
Uterine Perforation*