Korean J Obstet Gynecol.  1999 Jan;42(1):198-202.

A Case of metastatic choriocarcinoma diagnosed at 34th week of pregnancy

• Song CH
• Jung SM
• Yang WG
• Park JH
• Park WI
• Shin JW
• Joo JE

Abstract

Choriocarcinoma associated with a normal pregnancy is rare. Especially, choriocarcinoma coexistent with a viable pregnancy is even rarer and commonly presents with widespread metastatic disease. We experienced a patient at 34th week of pregnancy with dyspnea and sputum production due to pulmonary metastasis of choriocarcinoma. The serum B-hCG level was extremely elevated and the placenta had multifocal choriocarcinoma. After vaginal delivery, the patient was successfully treated with combination chemotherapy (EMA-CO). The patient is receiving follow up with monthly measurement of hCG values. We report one case of metastatic choriocarcinoma with viable pregnancy with review of literature.

Keyword

Metastatic Choriocarcinoma; Normal pregnancy

MeSH Terms

Choriocarcinoma*
Drug Therapy, Combination
Dyspnea
Female
Follow-Up Studies
Humans
Neoplasm Metastasis
Placenta
Pregnancy
Pregnancy*
Sputum