Korean J Obstet Gynecol.
1997 Jan;40(1):66-70.
A Study of a Molecular Variant of Angiotensinogen Associated with Korean Pregnancy-Induced Hypertension
Abstract
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Pregnancy-induced hypertension(PIH) is one of the major causes of maternal, fetal and neonatal morbidity and mortality. Although many causes are encountered, etiology of PIH is still unknown. A molecular variant of angiotensinogen, M235T, reported to be linked with essential hypertension and PIH. This study was to evaluate the molecular variation of angiotensinogen in Korean pregnancy-induced hypertension. Our results did not provide any definite relation with the molecular variant of angiotensinase, M235T, and Korean PIH.