- A Study of a Molecular Variant of Angiotensinogen Associated with Korean Pregnancy-Induced Hypertension
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Kim YT, Ku PS, Lee MS
- KMID: 2260712
- Korean J Obstet Gynecol.
- 1997 Jan;40(1):66-70.
Pregnancy-induced hypertension(PIH) is one of the major causes of maternal, fetal and neonatal morbidity and mortality. Although many causes are encountered, etiology of PIH is still unknown. A molecular variant... -
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- Lack of Association between Angiotensinogen M235T Gene Polymorphism and Ischemic Stroke in Korean
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Jea JS, Bang CO, Lee TK, Park HK, Ahn MY, Hong SY
- KMID: 1812912
- J Korean Neurol Assoc.
- 2001 Jan;19(1):24-28.
BACKGROUND: The associations between angiotensinogen M235T polymorphism and essential hypertension or ischemic stroke are still controversial. The aims of this study were to observe the associations of the angiotensinogen M235T... -
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- Tissue-Specific Regulation of Angiotensinogen and Angiotensin II Receptor Genes in Two-Kidney, One Clip Hypertensive Rats
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Lee JU, An MR, Nam SC, Kim WJ
- KMID: 1990051
- Korean J Nephrol.
- 1999 Jul;18(4):523-529.
The present study was aimed at investigating the molecular regulation of the renin- angiotensin system (RAS) in two-kidney, one clip (2K1C) hypertension. The expression of renin, angiotensinogen and angiotensin II receptor... -
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- Association of Angiotensin-Converting Enzyme and Angiotensinogen Gene Polymorphisms with Preeclampsia
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Choi H, Kang JY, Yoon HS, Han SS, Whang CS, Moon IG, Shin HH, Park JB
- KMID: 1733485
- J Korean Med Sci.
- 2004 Apr;19(2):253-257.
- doi: 10.3346/jkms.2004.19.2.253
We tested the hypothesis that angiotensin-converting enzyme (ACE) and angiotensinogen gene polymorphism influence the incidence, development and outcome of preeclampsia. Subjects were recruited from 90 Korean patients with preeclampsia during... -
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- Effects of Cyclosporine on the Intrarenal Renin-Angiotensin System
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Kim JS, An MR, Kim NH, Choi KC, Lee JU
- KMID: 2079022
- Korean J Nephrol.
- 1998 Sep;17(5):679-685.
The present study was aimed at investigating the effect of cyclosporine A (CsA) on the renal renin-angiotensin systems. In rats chronically treated with CsA, the intrarenal expression of various genes... -
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- Tissue-specific regulation of angiotensinogen and angiotensin II receptor gene expression in deoxycorticosterone acetate-salt hypertensive rats
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Lee JU, An MR
- KMID: 2285225
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):315-320.
Molecular regulation of the renin-angiotensin system (RAS) was investigated in deoxycorticosterone acetate (DOCA)-salt hypertension. The expression of renin, angiotensinogen and angiotensin II receptor genes in the kidney and liver was determined by Northern... -
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- Angiotensinogen, Thermolabile Methylenetetrahydrofolate Reductase and Factor V Gene Variants among Korean Women with Preeclampsia, as Risk Factors
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Ji IW, Park YJ, Jeong EH, Kim HS, Jang BW, Park YK
- KMID: 2272222
- Korean J Obstet Gynecol.
- 2004 Jan;47(1):60-67.
OBJECTIVE: To know the genotypic distributions of Angiotensinogen, Thermolabile Methylenetetrahydrofolate Reductase (MTHFR) and Factor V Gene Variants, suggested as risk factors of preeclampsia, among Korean Women. METHODS: 113 preeclampsia patients and... -
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- Change of Angiotensinogen mRNA Expression in Myocardium and Liver after Myocardial Infarction in Rat
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Kim HS
- KMID: 1751690
- Korean Circ J.
- 1999 Mar;29(3):322-334.
- doi: 10.4070/kcj.1999.29.3.322
BACKGROUND: The renin-angiotensin system (RAS) plays a crucial role in pathophysiology of congestive heart failure and ventricular remodeling after myocardial infarction (MI). There are two components, systemic and local, in... -
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- Change of Angiotensinogen mRNA in Rat Liver after Myocardial Infarction
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On YK, Oh SI, Kim SH, Kim YK, Kim HS, Kim CH, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS, Seo JD, Lee YW
- KMID: 1894826
- Korean Circ J.
- 1995 Apr;25(2):510-519.
- doi: 10.4070/kcj.1995.25.2.510
BACKGROUND: Loss of myocardium due to acute myocardial infarction may cause acute heart failure and future left ventricular dysfunction. During heart failure, homeostatic mechanism will be activated and the renin-angiotensin... -
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- Urinary Angiotensinogen Excretion and Intrarenal Angiotensinogen Expression in Minimal Change Disease Patients
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Jang HR, Jo A, Park JH, Lee JE, Huh W, Kim DJ, Oh HY, Kim YG
- KMID: 2141999
- Korean J Nephrol.
- 2011 Nov;30(6):593-600.
PURPOSE: Urinary angiotensinogen (AGT) has been reported as an important marker reflecting the activity of intrarenal renin-angiotensin system (RAS) in chronic glomerulonephritis patients. We investigated urinary AGT excretion and intrarenal... -
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- Angiotensinogen gene M235T polymorphism as a predictor of cardiovascular risk in hypertensive adolescents
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Gil JH, Lee JA, Park EY, Hong YM
- KMID: 2037334
- Korean J Pediatr.
- 2009 Jan;52(1):36-43.
- doi: 10.3345/kjp.2009.52.1.36
PURPOSE: The renin-angiotensin system (RAS) has been demonstrated to play a major role in regulating blood pressure. Therefore, components of the RAS are likely candidate genes that may predispose an... -
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- Angiotensinogen M235T and Essential Hypertension in Korea
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Hong SY, Bang CO, Kim CH, Kim HS, Yang DH, Choi JS, Ha KS
- KMID: 2254943
- Korean J Nephrol.
- 2000 May;19(3):455-460.
BACKGROUND: Potential involvement of the angiotensinogen gene(M235T) in the pathogenesis of essential hypertension has been suggested by some investigators. However, an association between M235T gene polymorphism and essential hypertension has... -
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- Colocalization of ANG II and mRNA for the Renin-Angiotensin System Components in Cultured Rat Glomerular Epithelial and Mesangial Cells
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Lee WJ, Ko CW, Park MJ
- KMID: 2030746
- Korean J Anat.
- 2002 Apr;35(2):105-111.
Mesangial cells are found to have renin and angiotensin II-AT1 receptors, but the presence of other components of the renin-angiotensin system and production of angiotensin II within the cell have... -
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- Molecular Biological Approach to Find Out the Etiology of Hypertensive Disorder in Pregnancy: Analysis of the Polymorphism in the Promoter of Human Angiotensinogen Gene in Korean Population
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Shim SS, Shim JY, Lim JH, Park JS, Jun JK, Bai KB, Yoon BH, Syn HC
- KMID: 2272119
- Korean J Obstet Gynecol.
- 2003 Aug;46(8):1486-1492.
OBJECTIVE: We undertook this study to find out general characteristics of hypertensive disorder in pregnancy and to clarify whether polymorphic marker of promoter region of angiotensinogen G(-6)A polymorphism is associated... -
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- A study on the association between angiotensinogen gene and angiotensin-converting-enzyme gene and pregnancy-induced hypertension in Korean women
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Kim YJ, Pang MG, Park MY, Park MH, Kim YW, Lee JS, Lee KS, Ahn JJ, Woo BH
- KMID: 2262259
- Korean J Obstet Gynecol.
- 2001 Jun;44(6):1072-1077.
OBJECTIVES: Previous studies have suggested an association of pregnancy-induced hypertension(PIH) with several genes involved in cardiovascular control. The objectives of this study were to evaluate the association between PIH and... -
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- Effects of angiotensin converting enzyme inhibition on gene expression of the renin-angiotensin system in rats
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Lee YR, Lee MY, Kim WJ, Lee WJ
- KMID: 2071836
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):771-778.
To investigate interaction of angiotensin converting enzyme (ACE) inhibitor with local tissue renin-angiotensin system (RAS), changes in gene expression of the RAS components in various tissues in response to chronic administration of an... -
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- Effect of hemorrhage on mRNA expressions of renin, angiotensinogen and AT-1 receptors in rat central and peripheral tissues
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Lee MK, Jo H, Kim KS, Yang EK, Lee WJ
- KMID: 1554551
- Korean J Physiol Pharmacol.
- 1997 Apr;1(2):151-159.
In an attempt to investigate whether hemorrhage affects the gene expression of the renin-angiotensin system (RAS) components in the brain and peripheral angiotensin-generating tissues, changes in mRNA levels of the RAS components in... -
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- Angiotensin converting enzyme I/D, angiotensinogen T174M-M235T and angiotensin II type 1 receptor A1166C gene polymorphisms in Turkish hypertensive patients
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Agachan B, Isbir T, Yilmaz H, Akoglu E
- KMID: 1119337
- Exp Mol Med.
- 2003 Dec;35(6):545-549.
Essential hypertension is a multifactorial disease in which genetic and enviromental factors play an important role. These factors differ in each population. As there are no existing data for the... -
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- Effects of Losartan on the Urinary Angiotensinogen Excretion in Chronic Non-diabetic Proteinuric Renal Disease
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Do YS, Choi SY, Jang EH, Kim YK, Baek H, Lee JE, Huh W, Kim DJ, Oh HY, Kim YG
- KMID: 2253310
- Korean J Nephrol.
- 2008 Mar;27(2):186-194.
PURPOSE: There were experimental evidences supporting that intrarenal activation of the renin-angiotensin system contributes to increase BP, proteinuria and urinary angiotensinogen (UAGT) excretion. The purpose of this prospective, open label,... -
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- Angiotensinogen M235T Polymorphism in Children with Henoch-Schonlein Purpura Nephritis
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Ha CW, Joo HJ, Park JK, Chung WY
- KMID: 2197648
- J Korean Soc Pediatr Nephrol.
- 2004 Apr;8(1):10-17.
PURPOSE: Henoch-Schonlein purpura(HSP) nephritis has a variable range of prevalence from 25 to 50% among HSP patients and is a common cause of chronic glomerulonephritis in children. In our study,... -
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