Korean J Med.  2011 Apr;80(4):371-377.

Recent Update of Pathology of the Pancreatic Neuroendocrine Tumor

Affiliations
  • 1Department of Pathology, Soonchunhyang University Hospital, Seoul, Korea.

Abstract

Pancreas is an endocrine organ as well as an exocrine one. The pancreatic neuroendocrine tumor (PNET) is an epithelial tumor with features of endocrine differentiation. Its incidence is progressively increasing now. Because the prognosis of PNET is much better than that of ductal adenocarcinoma, the precise diagnosis and proper treatment is more important than ever. Recently World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) published the new WHO 2010 classification and the unified staging system of the PNET unlike the other gastrointestinal tract. Here, recent update of pathology of PNET will be discussed with their basic morphologic characteristics and essential points in the pathology report.

Keyword

Pancreas; Chromogranin A; Pathology; Neuroendocrine tumor; Grading

MeSH Terms

Adenocarcinoma
Chromogranin A
Gastrointestinal Tract
Incidence
Joints
Neuroectodermal Tumors, Primitive
Neuroendocrine Tumors
Pancreas
Prognosis
World Health Organization
Chromogranin A
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