Korean J Med.  2009 Aug;77(2):255-260.

A case of combined herpes simplex virus, cytomegalovirus, and candidal esophagitis in an AIDS patient

• Kim HA
• Bae KH
• Ryu SY

Abstract

Since the first case of human immunodeficiency virus (HIV) infection was reported in Korea in 1985, the number of HIV patients has risen steadily and reached 5,323 in December 2007. Consequently, multiple opportunistic infections have become a significant clinical problem. Diseases of the gastrointestinal tract are among the most frequent complications of acquired immunodeficiency syndrome (AIDS) and cause morbidity in patients with HIV infection. Opportunistic infections are the leading cause of esophageal complaints. Candida albicans is the most frequently identified cause of esophageal symptoms, followed by herpes simplex virus (HSV) and cytomegalovirus (CMV) infections. Esophageal candidiasis often occurs concurrently with other infectious esophageal disorders. Simultaneous esophageal infection with HSV, CMV, and Candida spp. is rare. We report a case of combined HSV, CMV, and candidal esophagitis in an AIDS patient. He was treated with highly active antiretroviral therapy (HAART) and the appropriate antiviral and antifungal agents.

Keyword

Herpes simplex virus esophagitis; Candidal esophagitis; Cytomegalovirus esophagitis

MeSH Terms

Acquired Immunodeficiency Syndrome
Antifungal Agents
Antiretroviral Therapy, Highly Active
Candida
Candida albicans
Candidiasis
Cytomegalovirus
Esophagitis
Gastrointestinal Tract
Herpes Simplex
HIV
HIV Infections
Humans
Korea
Methylmethacrylates
Opportunistic Infections
Polystyrenes
Simplexvirus
Antifungal Agents
Methylmethacrylates
Polystyrenes