Korean J Gastrointest Endosc.  2010 Nov;41(5):280-284.

Simultaneous Herpes Simplex and Candida Esophagitis in Renal Transplant Patients

Affiliations
  • 1Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea. kimse@ewha.ac.kr

Abstract

Infectious esophagitis usually occurs in immunocompromised patients with AIDS, malignancy and those receiving immunosuppresive therapy. Common pathogens causing esophagitis include Candida, Herpes simplex virus and Cytomegalovirus. However simultaneous esophageal infection with both Candida and Herpes simplex virus has rarely been reported. The endoscopic findings of Herpes simplex esophagitis combined with Candida infection does not show typical findings due to diffuse whitish or yellowish plaques; hence, accurate diagnosis can be delayed. We observed concomitant infection of Herpes simplex virus and Candida causing esophagitis in a 45-year-old renal transplant patient who had been receiving immunosuppressive therapy. The patient showed marked reductions in clinical symptoms and in endoscopic findings after anti-fungal and acyclovir therapy.

Keyword

Esophagitis; Herpes simplex; Candida; Renal transplantation

MeSH Terms

Acyclovir
Candida
Cytomegalovirus
Esophagitis
Herpes Simplex
Humans
Immunocompromised Host
Kidney Transplantation
Methylmethacrylates
Middle Aged
Polystyrenes
Simplexvirus
Transplants
Acyclovir
Methylmethacrylates
Polystyrenes
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