Korean J Med.
2007 Jan;72(1):74-78.
An adenosquamous carcinoma of the liver that developed metachronously in a patient with a colon adenocarcinoma
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Inha University, Incheon, Korea.
- 2Department of Pathology, College of Medicine, Inha University, Incheon, Korea. ispap@inha.ac.kr
- 3Inha Research Institute for Medical Science, College of Medicine, Inha University, Incheon, Korea.
Abstract
- A primary adenosquamous carcinoma of the liver is a rare subtype of a cholangiocarcinoma. Adenosquamous carcinoma is known to have an aggressive biologic behavior and is associated with a poor prognosis. Recently, we experienced a case of a primary adenosquamous carcinoma of the liver. A 69-year-old man was subjected to a right hemicolectomy five months ago due to an ascending colon cancer. At a periodic check-up, abdominal ultrasonography and magnetic resonance imaging showed a ~1.1 cm-sized hepatic mass which was highly suspicious of being a hepatic metastasis from the ascending colon cancer. A hepatic segmentectomy was performed. The tumor was microscopically composed of an adenocarcinoma and a squamous cell carcinoma, and it was different from the previous colon cancer as determined by immunohistochemistry. Three months after the hepatic segmentectomy, multiple hepatic metastasis was found and the patient has been treated as an outpatient with capecitabine.
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