Korean J Bone Metab.  2011 Nov;18(2):125-130.

The Survey of Prevalence of Osteoporosis in Alzheimer's Disease Patients

• Kim Y
• Ahn KY
• Yoon TH
• Lim CJ
• Shin WJ

Abstract

OBJECTIVES
To evaluate the prevalence of osteoporosis in the Alzheimer's disease patients.
METHODS
One hundred and twenty eight patients with Alzheimer's disease were included in this study. The patients are diagnosed with Alzheimer's disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and BMD between 80 and 120 mg/cm3 is indicative osteopenia.
RESULTS
The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the Alzheimer's disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer's disease patients is 3.12%. The prevalence of severe osteoporosis fracture in the Alzheimer's disease patients is 32.03%.
CONCLUSION
The prevalence of osteoporosis in Alzheimer's disease patients is higher than in the control group.

Keyword

Alzheimer disease; Osteoporosis; Prevalence

MeSH Terms

Alzheimer Disease
Bone Density
Bone Diseases, Metabolic
Humans
Osteoporosis
Prevalence
Spine