Korean J Nephrol.  2005 May;24(3):460-463.

Multiple Renal Abscess by Extended-Spectrum beta-Lactamase Producing Escherichia coli

• Lim MK
• Kim KW
• Lee DK
• Lee HK
• Weon YD
• Kim YS
• Yoon SA
• Kim YO
• Chang YS

Abstract

Extended-spectrum beta-lactamase (ESBL) producing bacterial infection causes delayed response to antibiotic treatment and consequently results in serious problem, because it can hydrolyze the majority of beta-lactam antibiotics. Here we report a case of multiple renal abscess by ESBL producing Escherichia coli in a patient with diabetes mellitus who had a history of repetitive urinary tract infection. A 49-year old woman was admitted to our hospital because of intermittent fever, left flank pain, and vomiting. She had been diagnosed as acute pyelonephritis and treated with the first and third cephalosporin for 1 month at a clinic. At admission, urinary bacterial culture revealed Escherichia coli resistant to both the first and third cephalosporin such as cefotaxime, ceftriaxone, and ceftazidime. Double disk synergy test confirmed ESBL. Abdominal computed tomography demonstrated multiple renal abscess. After treatment of imipenam for 4 weeks, she discharged with improved condition.

Keyword

Renal abscess; Diabetes mellitus; Escherichia coli; ESBL

MeSH Terms

Abscess*
Anti-Bacterial Agents
Bacterial Infections
beta-Lactamases*
Cefotaxime
Ceftazidime
Ceftriaxone
Diabetes Mellitus
Escherichia coli*
Escherichia*
Female
Fever
Flank Pain
Humans
Middle Aged
Pyelonephritis
Urinary Tract Infections
Vomiting
Anti-Bacterial Agents
Cefotaxime
Ceftazidime
Ceftriaxone
beta-Lactamases