J Korean Acad Fam Med.  2004 Jun;25(6):475-480.

One Case of Systemic Lupus Erythematosus with Chief Complaint of Xerostomia and Abnormal Liver Function

• Yeon JW
• Baek SY
• Cho HW
• Shin YJ
• U DS
• Choi EJ
• Oh MK

Abstract

Dry mouth is a common symptom in over middle- aged women. Xerostomia itself can be caused by multifactorial etiolgy. Dry mouth may occur with the use of medications, as a complication of connective tissue and autoimmune disease, such as Sjogren's syndrome or sicca syndrome, with radiation therapy to the head and neck or diabetes mellitus, or with a number of other condition. Even stress and anxiety can lead to a dry mouth. Also, Abnormal liver function is associated with drugs, viral infection, alcohol, obesity, autoimmne disease and a number of other disease. A 41-year-old women complaining of xerostomia and known abnormal liver fuction since 1 year was admitted to our medical examination center. In this case, Final diagnosis was systemic lupus erythematosus with autoimmune hepatitis and secondary Sjogren's syndrome through characteristic clinical finding, liver biopsy, positive Schirmer's test, salivary gland biopsy, and salivary scintigraphy. The various immunosuppresant medication has taken and then liver function indices and clinical symptoms were improved.

Keyword

sytemic lupus erythematosus; autoimmune hepatitis; Sjogren's syndrome; xerostomia

MeSH Terms

Adult
Anxiety
Autoimmune Diseases
Biopsy
Connective Tissue
Diabetes Mellitus
Diagnosis
Female
Head
Hepatitis, Autoimmune
Humans
Liver*
Lupus Erythematosus, Systemic*
Mouth
Neck
Obesity
Radionuclide Imaging
Salivary Glands
Sjogren's Syndrome
Xerostomia*