Korean J Med.
2011 Mar;80(3):360-364.
A Case of Lupus-Related Hepatitis Mimicking Autoimmune Hepatitis
- Affiliations
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- 1Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. rapark@catholic.ac.kr
Abstract
- Patients with systemic lupus erythematosus (SLE) have a 25% to 50% incidence of abnormal findings on liver function tests. The main causes of abnormal liver function in patients with SLE are viral hepatitis, drug-induced toxic hepatitis, and fatty liver. However, hepatic involvement due to the pathogenic process of SLE is rare. In such conditions, lupus-related hepatitis must be distinguished from autoimmune hepatitis, which is a type of primary liver disease characterized by similar clinical manifestations and autoimmune profiles. Relationships between hepatic involvement of SLE and autoimmune hepatitis remain to be elucidated. We report a case of lupus-related hepatitis mimicking autoimmune hepatitis.