Korean J Gastroenterol.
2008 Mar;51(3):190-193.
A Case of Anti-LKM 1 Positive Autoimmune Hepatitis Accompanied by Systemic Lupus Erythematosus
- Affiliations
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- 1Department of Internal Medicine, Kwang Myung SungAe Hospital, Gwangmyeong, Korea. kimhkgi@naver.com
- 2Department of Internal Pathology, Kwang Myung SungAe Hospital, Gwangmyeong, Korea.
- 3Department of Internal Medicine, SunAe Hospital, Seoul, Korea.
Abstract
- Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti-LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis.
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