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Drug Induced Liver Injury by Prophylactic Administration of Albendazole

Moon SY, Baek YH, Lee SW

Albendazole is used as a typical antiparasitic agent worldwide. The side effects of albendazole may include nausea, vomiting, abdominal pain, dizziness, headache, alopecia, and increased liver enzymes. Mild elevation of...
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Do Natural Health Products Cause Toxic Hepatitis?

Ahn BM

Medicinal herb-induced liver injury reported on the literature ranges from mild elevation of liver enzymes to fulminant liver failure and liver cirrhosis. Medicinal herbs are common ingredients of traditional Chinese...
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Medicinal Herbs and Toxic Hepatitis

Ahn BM

Medicinal herb-induced liver injury reported on the literature ranges from mild elevation of liver enzymes to fulminant liver failure and liver cirrhosis. Medicinal herbs are common ingredients of traditional Chinese...
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Ombitasvir/paritaprevir/ritonavir+dasabuvir and ribavirin associated drug-induced liver injury and syndrome of inappropriate secretion of anti-diuretic hormone: A case report

Kumar R, Hsiang JC, Tan J, Thurairajah PH

No abstract available.
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A Case of Primaquine-Induced Acute Liver Failure

Jun MJ, Lee D, Choi YS, Kim EJ, Gong EJ, Chung YH

Primaquine was approved for treatment of malaria in 1952 by the United States Food and Drug Administration (FDA). It has remained the only FDA-licensed drug capable of clearing the intra-hepatic...
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Applicability of Two Clinical Scales for Causality Assessment in Acute Liver Injury Caused by Herbal Medicines or Health Tonics

Lee SH, Kim DH, Seo TJ, Cho S, Jung PJ, Park CH, Lee WS, Joo YE, Kim HS, Choi SK, Ryu JS, Kim SJ

  • KMID: 2274914
  • Chonnam Med J.
  • 2005 Aug;41(2):140-148.
There are no specific diagnostic markers for drug-induced liver injury. It is frequently diagnosed by subjective judgement of clinicians and the causal relationship is difficult to demonstrate. While causality assessment...
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Minocycline-Induced Autoimmune Hepatitis: A Rare But Important Cause of Drug-Induced Autoimmune Hepatitis

Harmon EG, McConnie R, Kesavan A

Drug-induced autoimmune hepatitis (DIAIH) is an increasingly recognized form of drug-induced liver injury that leads to a condition similar to idiopathic autoimmune hepatitis. A number of drugs have been associated...
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Active Pharmacovigilance of Drug-Induced Liver Injury Using Electronic Health Records

Kim SH

No abstract available.
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Methimazole-Induced Acute Cholestatic Hepatitis in a Patient with History of Simvastatin-Induced Liver Injury

Kwak MK, Kim SR, Park JW, Han SJ, Kim MJ, Jin SY, Kim HJ, Jang JY, Byun DW, Park HK

Methimazole and prophylthiouracil are commonly prescribed for patients with hyperthyroidism. The serious side effect of toxic hepatitis caused by these two drugs is well known. According to recent Korean and...
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Factors affecting drug-induced liver injury: antithyroid drugs as instances

Heidari R, Niknahad H, Jamshidzadeh A, Abdoli N

Methimazole and propylthiouracil have been used in the management of hyperthyroidism for more than half a century. However, hepatotoxicity is one of the most deleterious side effects associated with these...
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Effects of Active Hexose Correlated Compounds on Drug Induced Liver Injury in Mice

Min KO, Kwon HJ, Seo EJ, Kim J, Kang SJ, Kim BK

  • KMID: 1725704
  • Korean J Pathol.
  • 2000 Jul;34(7):509-515.
AHCC (Active Hexose Correlated Compounds), which was at first extracted from cultured broth of Basidiomycotina, is known to be one of the Biological Response Modifiers (BRM). We examined the protective...
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A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage

Kim JS, Jang YR, Lee JW, Kim JY, Jung YK, Chung DH, Kwon OS, Kim YS, Choi DJ, Kim JH

Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present...
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Drug-induced liver injury: present and future

Suk KT, Kim DJ

Liver injury due to prescription and nonprescription medications is a growing medical, scientific, and public health problem. Worldwide, the estimated annual incidence rate of drug-induced liver injury (DILI) is 13.9-24.0...
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Successful salvage treatment of acute graft-versus-host disease after liver transplantation by withdrawal of immunosuppression: a case report

Qiu W, Lv GY, Jiang C, Zhang P, Sun XD, Shi XJ, Liu XY, Wang GY

Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported...
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Drug Induced Liver Disease Caused by Ingestion of Dyctamnus dasycarpus

Paik SW, Rhee JC, Kim JJ, Koh KC, Lee HY, Rhee PL, Lee JH, Lee JK, Oh YR, Chi YJ

  • KMID: 2240652
  • Korean J Gastroenterol.
  • 1998 Feb;31(2):251-257.
Although drug induced liver injury caused by herbal medicine is considered to be a frequent problem in Korea, there are only a few reports concerning the hepatotoxicity of herbal medicine....
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A Case of Acute Pancreatitis and Acute Hepatitis Caused by Ingestion of Ceramium kondoi

Kim DB, Cho YK, Song HJ, Song BC

In Korea, the use of herbal remedies is a common cause of drug-induced liver injury. However, the occurrence of both acute pancreatitis and acute hepatitis after taking herbal remedies has...
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Clozapine-Induced Acute Hepatitis

Jang SJ, Yi HT, Paek JH, Lee SY

  • KMID: 2340279
  • J Korean Neuropsychiatr Assoc.
  • 1999 Jan;38(1):227-233.
The authors report two cases of clozapine-induced acute hepatitis. Two patients developed asymptomatic hepatitis and got better with conservative care. We decreased the dosage of clozapine and added hepatic protectors,...
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A Case of Acute Liver Failure Associated with Methimazole in Patient with Underlying Liver Disease

Lee JE, Kim YA, Kim LK, Park YJ

We report a case of methimazole-induced acute hepatic failure, which occurred 4 days after initiation of drug in a 51-year-old man with hyperthyroidism. Liver function was evaluated before taking methimazole,...
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Genetic polymorphisms of interleukin-10 and transforming growth factor-β1 and antituberculosis drugs-induced liver injury

Jung S, Kim SH, Sohn JW, Yoon HJ, Shin DH, Jee YK, Kim SH

PURPOSE: Drug-induced liver injury is one of the serious adverse reactions resulting in severe morbidity and discontinuation of medications. Previously, IL-10 gene polymorphism has been reported to be associated with...
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Unresolved Issues of Drug-Induced Liver Injury

Kim DJ

  • KMID: 2263941
  • Korean J Med.
  • 2011 Jul;81(1):50-52.
Liver injury due to prescription and nonprescription medications is a growing medical, scientific, and public health problem. Worldwide, the estimated annual incidence rate of Drug-induced liver injury (DILI) is 13.9-24.0...
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