Korean J Hepatol.
2011 Sep;17(3):229-232. 10.3350/kjhep.2011.17.3.229.
A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
- Affiliations
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- 1Department of Internal Medicine, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea. 93cool@hanmail.net
- 2Department of Pathology, Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea.
- KMID: 1025204
- DOI: http://doi.org/10.3350/kjhep.2011.17.3.229
Abstract
- Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient's symptoms improved and her liver enzyme levels reduced to near to the normal range.
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