Korean J Nephrol.  2010 Sep;29(5):634-637.

Nephrotic Syndrome Disappeared after Gemcitabine Combination Therapy in a Patient with Progressive Non-small Cell Lung Cancer

Affiliations
  • 1Department of Medical Oncology & Hematology, East-West Neo Medical Center, Kyung Hee University, Seoul, Republic of Korea. lj2lj2@hanmail.net
  • 2Department of Nephrology, East-West Neo Medical Center, Kyung Hee University, Seoul, Republic of Korea.
  • 3Department of Respiratory and Critical Care Medicine, East-West Neo Medical Center, Kyung Hee University, Seoul, Republic of Korea.
  • 4Department of Pathology, East-West Neo Medical Center, Kyung Hee University, Seoul, Republic of Korea.

Abstract

Nephrotic syndrome has been reported to accompany a malignancy. Since the first case of the nephrotic syndrome associated with extra-renal malignancy was reported in 1922, only a few cases of nephrotic syndrome accompanying other malignancies have been reported. Previous reports on such cases indicated a pattern of improvement in nephropathy as malignancy improved. But the cases of resolved nephropathy with aggravated cancer have scarcely been documented. Here we report a case of a 69 year-old male with nephrotic syndrome accompanying non-small cell lung cancer, whose proteinuria was normalized after chemotherapy while his cancer was aggravated.

Keyword

Nephrotic syndrome; Non-small cell lung carcinoma; Chemotherapy; Gemcitabine

MeSH Terms

Carcinoma, Non-Small-Cell Lung
Deoxycytidine
Humans
Male
Nephrotic Syndrome
Proteinuria
Deoxycytidine
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