Korean J Med.  2003 Nov;65(Suppl 3):S890-S893.

A case of klebsiella ornithinolytica bacteremia

Affiliations
  • 1Division of Infectious Diseases, Asan Medical Center, Ulsan University Hospital, University of Ulsan College of Medicine, Seoul, Korea. njkim@amc.seoul.kr
  • 2Department of Laboratory Medicine, Asan Medical Center, Ulsan University Hospital, University of Ulsan College of Medicine, Seoul, Korea.
  • 3Division of Infectious Diseases, Ulsan University Hospital, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Klebsiella ornithinolytica is a very rare Klebsiella species isolated from human. Human strains have been isolated mainly from respiratory secretions, wounds and urine. The clinical features and pathogenic role of human disease with K. ornithinolytica is unknown. We describe a case of K. ornithinolytica bacteremia which developed in a 45-year-old man with acute cholangitis by common bile duct stones. In this case, K. ornithinolytica was sensitive to beta-lactamase inhibitor, all tested cephalosporins, aminoglycosides, quinolones, trimethoprim/sulfameth- oxazole but resistant to ampicillin. After intravenous therapy with cefotaxime, follow up blood culture showed no further growth of K. ornithinolytica. Later, extended-spectrum beta-lactamase (ESBL) producing Klebsiella pneumoniae and Escherichia coli was cultured from bile, so the antibiotics was switched to meropenem. Common bile duct stones was removed by percutaneous transhepatic cholangioscopy (PTCS) and the patient recovered fully without any complication.

Keyword

Klebsiella; Bacteremia; Cholangitis

MeSH Terms

Aminoglycosides
Ampicillin
Anti-Bacterial Agents
Bacteremia*
beta-Lactamases
Bile
Cefotaxime
Cephalosporins
Cholangitis
Common Bile Duct
Escherichia coli
Follow-Up Studies
Humans
Klebsiella pneumoniae
Klebsiella*
Middle Aged
Quinolones
Wounds and Injuries
Aminoglycosides
Ampicillin
Anti-Bacterial Agents
Cefotaxime
Cephalosporins
Quinolones
beta-Lactamases
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