Korean J Nephrol.
2011 Jul;30(4):399-403.
A Case of Minimal Change Nephrotic Syndrome Presented as Portal Vein Thrombosis and Acute Renal Failure
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. mazzang2848@naver.com
- 2Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- Patients with the nephrotic syndrome are at risk of developing thromboembolic complications. Much evidence suggests that a hypercoagulable state exists in the setting of the nephrotic syndrome, but the exact mechanisms are poorly understood. The nephrotic syndrome associated with portal vein thrombosis is relatively uncommon. We experienced a case of minimal change nephrotic syndrome presented as portal vein thrombosis and acute renal failure. On renal biopsy, electron microscopic examination reveals diffuse foot process effacement. Treatment with corticosteroid and anticoagulation resulted in complete remission of proteinuria.
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