Korean J Med.  2005 May;68(5):581-586.

A case of pulmonary embolism occured after injection of bovine collagen

• Lee JS
• Kim DY
• Hwang SJ
• Baek SS
• Jang YS
• Kim HJ
• Ahn CM

Abstract

Collagen and its products, used in some medical field are relatively safe but may induce hypersensitivity reaction. However, pulmonary embolism is a rare but serious complication after injection of them. A-48-year old woman was admitted because of cough, hemoptysis and dyspnea. Nine days ago, she had received breast augmentation with injectable collagen by unlicensed person. Four days later, she experienced cough, hemoptysis and dyspnea. On admission right side pleural effusion and peripheral distributed diffuse consolidations in both lungs were noted on chest radiograph. A computed tomographic (CT) scan of the chest showed non-segmental distribution of bilateral ground-glass opacity and interlobular septal thickening with multifocal consolidation in both lungs. Sputum and urine cytologic examination revealed foamy histiocytes containing lipid vaculoes. Conservative management was done under the impression of pulmonary embolism after collagen injection. She was dischared with full recovery. Here, we report a case of pulmonary embolism occurred after infection of collagen first in Korea.

Keyword

Pulmonary embolism; Collagen

MeSH Terms

Breast
Collagen*
Cough
Dyspnea
Female
Hemoptysis
Histiocytes
Humans
Hypersensitivity
Korea
Lung
Pleural Effusion
Pulmonary Embolism*
Radiography, Thoracic
Sputum
Thorax
Collagen