Korean J Dermatol.  2003 Jan;41(1):85-88.

Three Cases of Clear Cell Acanthoma on Nipple and Areola

Affiliations
  • 1Department of Dermatology, College of Medicine, Gyeongsang National University, Chinju, Korea. deroh@nongae.gsnu.ac.kr
  • 2Gyeongsang Institute of Health Science, Gyeongsang National University, Chinju, Korea.

Abstract

Clear cell acanthoma is a relatively uncommon benign disease, which usually presents as solitary lesions, often localized on the lower legs of middle aged or elderly individuals1. Clinically it presents as a flat or dome-shaped, sharply demarcated papule or nodule. Histopathologic findings are composed of clear cells within sharply demarcated area of the epidermis. We report three cases of clear cell acanthoma developed on the nipples and areolar areas of the young women. These cases should be differentiated from various diseases showing clinically benign eczematous feature. In conclusion, clear cell acanthoma could be included in the differential diagnosis of eczema, and it is suggested that biopsies specimen should include the lesion as well as the normal tissue.

Keyword

Clear cell acanthoma; Nipple; Areola

MeSH Terms

Acanthoma*
Aged
Biopsy
Diagnosis, Differential
Eczema
Epidermis
Female
Humans
Leg
Middle Aged
Nipples*
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