Yeungnam Univ J Med.  2015 Dec;32(2):111-113. 10.12701/yujm.2015.32.2.111.

Clear cell acanthoma on areola

• Kim BS
• Kim YW
• Choi JH
• Sohng SH
• Shin DH
• Choi JS

• KMID: 2319910
• DOI: http://doi.org/10.12701/yujm.2015.32.2.111

Abstract

Clear cell acanthoma (CCA) is an asymptomatic benign lesion of unknown origin that typically appears as a brownish, dome-shaped papule on the leg. It has an unusual clinical feature in that it appears as chronic eczema, Bowen disease, or Paget disease on the areola. Its histopathologic findings are well-demarcated psoriasiform acanthosis with pale keratinocytes (clear cells) that are rich in intracellular glycogen, which stain positively with Periodic acid-Shiff. We report herein on a young female patient with CCA on the areolar areas.

Keyword

Acanthoma; Clear cell acanthoma; Nipples

MeSH Terms

Acanthoma*
Bowen's Disease
Eczema
Female
Glycogen
Humans
Keratinocytes
Leg
Nipples
Glycogen