Korean J Infect Dis.
1997 May;29(3):257-261.
A Case of Scleredema Preceded by Upper Respiratory Infection
- Affiliations
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- 1Department of Internal Medicine, and Dermatology, National Police Hospital, Seoul, Korea.
Abstract
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Scleredema is a rare connective tissue disease of unknown etiology and characterized by non-pitting thickening of subcutaneous tissue of the neck, face, head, upper trunk and arms. We present a 28 year-old man with extensive skin changes following upper respiratory infection, who have not any concurrent disorders such as diabetes mellitus. Histopathological findings of skin showed normal epidermis with a widening of spaces between collagen bundles by infiltration of acid mucopolysaccharide in the dermis.