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Emerging Nondopaminergic Medications for Parkinson’s Disease: Focusing on A2A Receptor Antagonists and GLP1 Receptor Agonists

Shang P, Baker M, Banks S, Hong SI, Choi DS

Parkinson’s disease (PD) is a severe neurodegenerative disease characterized by classic motor features associated with the loss of dopaminergic neurons and appearance of Lewy bodies in the substantia nigra. Due...
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The Development of Antibody-Drug Conjugates for Urothelial Carcinoma Treatment

Choi DS, Kang SJ, Chang IH, Choi YW

Urothelial cancer is the seventh most common cancer among men worldwide. Bacille de Calmette-Guérin is a type of anticancer immunotherapy that has been used to treat targeted bladder cancer, but...
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Modulating Effects of Whole-body Vibration on Cortical Activity and Gait Function in Chronic Stroke Patients

Lee A, Kim H, Kim J, Choi DS, Jung JH, Lee J, Kim YH

Whole-body vibration exercise (WBVe) can provide proper somatosensory stimulation and improve muscle strength in stroke patients. This study investigated the effects of WBVe on gait function and cortical activity in...
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Rodent models for psychiatric disorders: problems and promises

Baker M, Hong SI, Kang S, Choi DS

Psychiatric disorders are a prevalent global health problem, over 900 million individuals affected by a continuum of mental and substance use disorders. Due to this high prevalence, and the substantial...
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Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice

Choi DS, Ji Y, Jang Y, Lee WJ, Shim WS

Crotamiton is an anti-scabies drug, but it was recently found that crotamiton also suppresses non-scabietic itching in mice. However, the underlying mechanism is largely unclear. Therefore, aim of the study...
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Chewing performance in orthodontic patients treated with extraction of premolars

Jang I, Jang E, Choi DS, Cha BK

The purpose of the present study was to evaluate the kinematic parameters of the chewing cycles in patients who had undergone comprehensive orthodontic treatment with extraction of premolars and to...
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Application of the foramina of the trigeminal nerve as landmarks for analysis of craniofacial morphology

Lim BD, Choi DS, Jang I, Cha BK

OBJECTIVE: The objective of this study was to develop new parameters based on the foramina of the trigeminal nerve and to compare them with the conventional cephalometric parameters in different...
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Arterial Spin Labelling Perfusion, Proton MR Spectroscopy and Susceptibility-Weighted MR Findings of Acute Necrotizing Encephalopathy: a Case Report

Kwon H, Choi DS, Jang J

In this study, we report arterial spin labelling perfusion, proton MR spectroscopy and susceptibility-weighted MR findings of acute necrotizing encephalopathy in a child with rotavirus infection.
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Susceptibility-Weighted MR Imaging for the Detection of Isolated Cortical Vein Thrombosis in a Patient with Spontaneous Intracranial Hypotension

Kwon H, Choi DS, Jang J

Spontaneous intracranial hypotension (SIH) can be a rare risk factor of cerebral venous thrombosis. We describe a case of isolated cortical vein thrombosis (CVT) secondary to SIH and discuss the...
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Pierre Robin sequence with severe scoliosis in an adult: A case report of clinical and radiological features

Kim JJ, Choi DS, Jang I, Cha BK, Park IW

Pierre Robin sequence (PRS) is characterized by the triad of micrognathia, glossoptosis, and airway obstruction. PRS does not have a single pathogenesis, but rather is associated with multiple syndromes. This...
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Botulinum toxin-A injection into the anterior belly of the digastric muscle for the prevention of post-operative open bite in class II malocclusions: a case report and literature review

Kang YJ, Cha BK, Choi DS, Jang IS, Kim SG

BACKGROUND: Class II malocclusion patients with hyperdivergent facial types are characterized by short mandibular body lengths and anterior open bite. Accordingly, the treatment for hyperdivergent skeletal class II malocclusion is...
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Current status of the surgery-first approach (part I): concepts and orthodontic protocols

Choi DS, Garagiola , Kim SG

The “surgery-first” approach, defined as a team approach between surgeons and orthodontists for orthognathic surgery without preoperative orthodontic treatment, is aimed at dental decompensation. A brief historical background and indications...
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Clinical application of an intraoral scanner for serial evaluation of orthodontic tooth movement: A preliminary study

Yun D, Choi DS, Jang I, Cha BK

The aim of this study was to test the clinical application of an intraoral scanner for serial evaluation of orthodontic tooth movement. The maxillary dentitions of eight patients with fixed...
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Characteristics of mass casualty chemical incidents: a case series

Kim S, Park JH, Park JO, Hong KJ, Choi DS, Kim TH, Jeong J, Song SW, Song KJ, Shin SD

OBJECTIVE: The aim of this study was to evaluate the characteristics of the emergency medical services (EMS) response and clinical information on mass casualty chemical incidents in Korea. METHODS: This retrospective...
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Prevalence and Associated Risk Factors of Sarcopenia in Female Patients with Osteoporotic Fracture

Yoon BH, Lee JK, Choi DS, Han SH

BACKGROUND: We determined the prevalence of sarcopenia according to fracture site and evaluated the associated risk factors in female patients with osteoporotic fractures. METHODS: A total of 108 patients aged 50...
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Understanding Gender and Transgender

Choi DS, Park BR, Lee ES

In the binary of gender, women and femininity came to be associated with motherhood, nurturing, and beauty whilst men and masculinity were associated with productivity, protection, and strength. No longer...
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Multiple Sequential Physeal Injuries with Vitamin D Deficiency

Kim BK, Kim YG, Lee HJ, Choi DS, Dan J

Vitamin D plays a major role in bone metabolism, and its deficiency has an impact on fracture risk and healing. Low vitamin D levels are a cause of poor bone...
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Hip Arthroplasty Using the Bencox® Hip System: An Evaluation of a Consecutive Series of One Thousand Cases

Lee JM, Sim YS, Choi DS

PURPOSE: This is a report on the outcomes associated with a consecutive series of 1,000 cementless hip arthroplasties utilizing the Bencox® hip stem–the first Korean-developed hip prosthesis. MATERIALS AND METHODS: A...
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Ten-Year Mortality Trends for Adults with and without Diabetes Mellitus in South Korea, 2003 to 2013

Kim KJ, Kwon TY, Yu S, Seo JA, Kim NH, Choi KM, Baik SH, Choi DS, Kim SG, Park Y, Kim NH

BACKGROUND: To estimate and compare the trends of all-cause and cause-specific mortality rates for subjects with and without diabetes in South Korea, from 2003 to 2013. METHODS: Using a population-based cohort...
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Aberrant growth of the anterior cranial base relevant to severe midface hypoplasia of Apert syndrome

Cha BK, Choi DS, Jang IS, Yook HT, Lee SY, Lee SS, Lee SK

BACKGROUND: A 9-year-old male showed severe defects in midface structures, which resulted in maxillary hypoplasia, ocular hypertelorism, relative mandibular prognathism, and syndactyly. He had been diagnosed as having Apert syndrome...
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