Korean J Dermatol.  2008 May;46(5):670-673.

A Case of Piloleiomyoma Arising in a BCG Vaccination Site

• Kim SW
• Choi WS
• Kang YS
• Lee UH
• Park HS
• Jang SJ

Abstract

BCG is a live attenuated vaccine derived from Mycobacterium bovis. It can give rise to several cutaneous complications including benign and malignant tumors. There are many reports about tumors arising in vaccination sites, especially those of small pox and BCG vaccinations. Reported tumors are basal cell carcinoma, dermatofibroma, melanoma, pilomatricoma and so on. Piloleiomyoma is a rare soft tissue tumor arising from arrector pili muscles. Clinically, piloleiomyomas appear as firm dermal papules and nodules with skin colored, pink, or reddish-brown surfaces. We experienced a case of piloleiomyma arising in a BCG vaccination site, which has not been reported in previous literature. Although several hypotheses have been propsed, there are no identified causes of leiomyoma. Trauma by the vaccination, persistent inflammation, wound healing process, or antigenic stimulation of the innoculation agent could be the possible causes in this case.

Keyword

BCG vaccination; Complications; Piloleiomyoma

MeSH Terms

Carcinoma, Basal Cell
Histiocytoma, Benign Fibrous
Inflammation
Leiomyoma
Melanoma
Muscles
Mycobacterium bovis
Pilomatrixoma
Skin
Vaccination
Wound Healing