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The Profile of Early Sedation Depth and Clinical Outcomes of Mechanically Ventilated Patients in Korea

Hyun Dg, Ahn JH, Gil HY, Nam CM, Yun C, Lee JM, Kim JH, Lee DH, Kim KH, Kim DJ, Lee SM, Ryu HG, Hong SK, Kim JB, Choi EY, Baek J, Kim J, Kim EJ, Park TY, Kim JH, Park S, Park CM, Jung WJ, Choi NJ, Jang HJ, Lee SH, Lee YS, Suh GY, Choi WS, Lee KS, Kim HW, Min YG, Lee SJ, Lim CM

Background Current international guidelines recommend against deep sedation as it is associated with worse outcomes in the intensive care unit (ICU). However, in Korea the prevalence of deep sedation and its...
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XperCT-guided Intra-cisterna Magna Injection of Streptozotocin for Establishing an Alzheimer’s Disease Model Using the Cynomolgus Monkey (Macaca fascicularis)

Park J, Won J, Jeon CY, Lim KS, Choi WS, Park Sh, Seo J, Cho J, Seong JB, Yeo HG, Kim K, Kim YG, Kim M, Yi KS, Lee Y

  • KMID: 2537960
  • Exp Neurobiol.
  • 2022 Dec;31(6):409-418.
  • doi: 10.5607/en22027
Till date, researchers have been developing animal models of Alzheimer’s disease (AD) in various species to understand the pathological characterization and molecular mechanistic pathways associated with this condition in humans...
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Feasibility of Loop-Mediated Isothermal Amplification for Rapid Detection of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Tissue Samples

Kim SG, Choi GW, Choi WS, Lim CS, Jang WS, Bae JH

Background: To date, few studies have investigated the feasibility of the loop-mediated isothermal amplification (LAMP) assay for identifying pathogens in tissue samples. This study aimed to investigate the feasibility of...
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Amisulpride Augmentation in Schizophrenia Patients with Poor Response to Olanzapine: A 4-week, Randomized, Rater-Blind, Controlled, Pilot Study

Woo YS, Park SY, Yoon BH, Choi WS, Wang SM, Bahk WM

Objective: The purpose of this study was to compare the efficacy and tolerability of continued olanzapine (OLA) versus amisulpride (AMI) augmentation in schizophrenic patients with poor response to OLA monotherapy. Methods:...
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Benzyl Isothiocyanate-Induced Cytotoxicity via the Inhibition of Autophagy and Lysosomal Function in AGS Cells

Po WW, Choi WS, Khing TM, Lee JY, Lee JH, Bang JS, Min YS, Jeong JH, Sohn UD

Gastric adenocarcinoma is among the top causes of cancer-related death and is one of the most commonly diagnosed carcinomas worldwide. Benzyl isothiocyanate (BITC) has been reported to inhibit the gastric...
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Changing Trends in Sexual Debut Age in the Korean Internet Sexuality Survey

Park J, Park SH, Lee SJ, Song WH, Choi WS, Cho MC, Son H

Purpose: To evaluate changing trends in relation to the sexual debut age and socioeconomic status (SES) in Korea. Materials and Methods: The Korean Internet Sexuality Survey (KISS) was conducted for in...
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Infectivity of Coronavirus Disease 2019: A Prospective Cohort Study in the Korean Metropolitan Area

Seok H, Lim S, Kim JY, Park CH, Kim JH, Woo ML, Won H, Kang YM, Oh HS, Song KH, Jung YJ, Kim T, Jo S, Choi WS

Background: Although several characteristics of coronavirus disease 2019 (COVID-19), an ongoing pandemic disease, have been identified, data on the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are limited. Methods:...
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Protective Role of Microglia on Neuronal Survival after Exposure to Amyloid Beta

Lee S, Choi WS

Alzheimer’s disease (AD) is the most common cause of neurodegeneration. It is characterized by deposits of amyloid beta (Aβ) plaques and impaired memory. Microglia are associated with AD. They are...
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Improved motility in the gastrointestinal tract of a postoperative ileus rat model with ilaprazole

Kim GM, Sohn HJ, Choi WS, Sohn UD

Postoperative ileus (POI), a symptom that occurs after abdominal surgery, reduces gastrointestinal motility. Although its mechanism is unclear, POI symptoms are known to be caused by inflammation 6 to 72...
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Sudden cardiac death as a naturally-occurring ventricular hypertrophy in Macaca fascicularis

Yeo HG, Park J, Kim HK, Lee JM, Koo BS, An JH, Jeon CY, An YJ, Choi WS, Park SH, Seo J, Won J, Kim K, Cho J, Kim YG, Kim M, Seong JB, Huh JW, Kim SS, Lee Y, Lim KS

Naturally occurring left ventricular hyperplasia is a rare but lethal disease. There are very few reports of this cardiac disease in captive nonhuman primates. In a colony of Macaca mulatta...
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Investigation of Information Acquisition Channel for Prostate Cancer High-Risk Group

Ha YS, Kim KT, Nam W, Park H, Yoo S, Lee CH, Chung HS, Choi WS, Kim J, Shin J, Kim JH, Kwak C

Purpose: The survey was conducted on Korean men to examine information acquisition channel for prostate cancer high risk group as part of the “Blue Ribbon Campaign” of the Korean Urological...
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2021 Clinical Practice Guidelines for Diabetes Mellitus in Korea

Hur KY, Moon MK, Park JS, Kim SK, Lee SH, Yun JS, Baek JH, Noh J, Lee BW, Oh TJ, Chon S, Yang YS, Son JW, Choi JH, Song KH, Kim NH, Kim SY, Kim JW, Rhee SY, Lee YB, Jin SM, Kim JH, Kim CH, Kim DJ, Chun S, Rhee EJ, Kim HM, Kim HJ, Jee D, Kim JH, Choi WS, Lee EY, Yoon KH, Ko SH, Committee of Clinical Practice Guidelines, Korean Diabetes Association

The Committee of Clinical Practice Guidelines of the Korean Diabetes Association (KDA) updated the previous clinical practice guidelines for Korean adults with diabetes and prediabetes and published the seventh edition...
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Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches

Thein W, Po WW, Choi WS, Sohn UD

The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the...
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Effects of the Combination of Evogliptin and Leucine on Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice

Shin CY, Lee HY, Kim GH, Park SY, Choi WS, Sohn UD

In this study, we aimed to investigate the effects of 8 weeks of treatment with a combination of evogliptin and leucine, a branchedchain amino acid, in mice with high-fat diet...
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Practice Pattern of Redo Varicocelectomy for Recurrent Varicocele according to Type of Initial Treatment: Retrospective Analysis of a United States-Based Insurance Claims Database

Park HK, Min GE, Chung KJ, Li S, Choi WS, Chung BI

Purpose: The objective of this study was to investigate the type of redo varicocelectomy according to the initial surgery type using a large population of USA insurance data. Materials and Methods:...
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Increasing Individual Target Glucose Levels to Prevent Hypoglycemia in Patients with Diabetes

Shin J, Kim H, Kim HS, Kim C, Choi WS

Hypoglycemia is one of the severe complications of diabetes. To prevent hypoglycemia, an emphasis is placed on maintaining an appropriate balance between nutrition, activity, and treatment, which can be achieved...
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Analysis of mortality risk by age-group of patients who visit the emergency room due to suicidal attempts

Moon JY, Cho JS, Choi WS, Choi JY, Jang JH, Woo JH, Lim YS

  • KMID: 2517700
  • J Korean Soc Emerg Med.
  • 2021 Jun;32(3):205-213.
Objective: Previous studies lacked an accurate analysis of age-specific mortality because they included either a single hospital’s data or survey-based method, rather than the patient’s information from the emergency room...
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Factors associated with injury severity among users of powered mobility devices

Choi SW, Woo JH, Hyun SY, Jang JH, Choi WS

Objective To examine the features of powered mobility device-related injuries and identify the predictors of injury severity in such settings. Methods Emergency Department-based Injury In-depth Surveillance data from 2011 to 2018...
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Korean Society of Infectious Diseases/National Evidence-based Healthcare Collaborating Agency Recommendations for Anti-SARSCoV-2 Monoclonal Antibody Treatment of Patients with COVID-19

Kim SB, Kim J, Huh K, Choi WS, Kim YJ, Joo EJ, Kim YJ, Yoon YK, Heo JY, Seo YB, Jeong SJ, Yu SY, Peck KR, Choi M, Yeom JS, Korean Society of Infectious Diseases (KSID)

Neutralizing antibodies targeted at the receptor-binding domain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein have been developed and now under evaluation in clinical trials. The US Food...
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Comprehensive Understanding and Field Application of COVID-19 Vaccine

Choi WS

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