Korean J Dermatol.
2009 Apr;47(4):459-462.
A Case of Nicolau Syndrome Treated with Non-steroidal Anti-inflammatory Drug Injection Therapy
- Affiliations
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- 1Department of Dermatology, Eulji Hospital, College of Medicine, Eulji University, Seoul, Korea. ssjmdderma@eulji.ac.kr
Abstract
- Nicolau syndrome, also known as livedoid dermatitis or embolia cutis medicamentosa, is a rare cutaneous adverse drug reaction characterized by the acute onset of cutaneous and soft-tissue necrosis following intramuscular drug injection. The typical presentation is pain around the injection site, developing into erythema, a livedoid patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. We report a 72-year-old man who presented with a painful, erythematous patch on his left buttock. The patient was treated with non-steroidal anti-inflammatory drug (diclofenac sodium) injection.
