Korean J Dermatol.
2009 Apr;47(4):435-438.
A Case of Osteoma Cutis, a Diagnostic Clue for Albright's Hereditary Osteodystrophy
- Affiliations
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- 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. juhee@yuhs.ac
Abstract
- Albright's hereditary osteodystrophy (AHO) has a broad spectrum of physical findings, including short stature, flattened nasal bridge, round facies, obesity, skeletal anomalies of the hands with brachydactyly, osteoma cutis, mental retardation, dental defects, cataracts, and calcification in the basal ganglia. It also includes endocrinologic abnormalities such as pseudohypoparathyroidism and pseudopseudohypoparathyroidism. Primary osteoma cutis, which can precede other physical findings of AHO, might be a diagnostic clue for AHO. Therefore, close follow-up and regular laboratory tests should be done to detect the early development of AHO in young children with primary osteoma cutis. Early diagnosis and treatment of AHO can prevent irreversible mental retardation and developmental delay.
MeSH Terms
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Basal Ganglia
Bone Diseases, Metabolic
Brachydactyly
Cataract
Child
Early Diagnosis
Facies
Fibrous Dysplasia, Polyostotic
Hand
Humans
Intellectual Disability
Obesity
Ossification, Heterotopic
Osteoma
Pseudohypoparathyroidism
Pseudopseudohypoparathyroidism
Skin Diseases, Genetic
Bone Diseases, Metabolic
Fibrous Dysplasia, Polyostotic
Ossification, Heterotopic
Skin Diseases, Genetic
