Korean J Dermatol.
2009 May;47(5):576-579.
Treatment of Acne with Isotretinoin in a Patient with Apert's Syndrome
- Affiliations
-
- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. knderma@catholic.ac.kr
- 2Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- Apert's syndrome is a rare autosomal dominant disease that's characterized by craniosynostosis and severe syndactyly of both the hands and feet. It is caused by a mutation of the fibroblast growth factor receptor (FGFR) type-2 gene. The development of widespread acne, involving the face, chest, back and forearms, is a characteristic finding at puberty in Apert's syndrome patients. The acne of Apert's syndrome patients is generally resistant to conventional therapy, including topical agents and/or oral antibiotics, but it shows a good response to isotretinoin. We report here on a case of acne that was successfully treated with isotretinoin in a teenager with Apert's syndrome.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Isotretinoin Treatment for the Recalcitrant Acne on a Patient with Apert Syndrome
- Severe Hyperhidrosis in Apert Syndrome: A Case Report
- 13-cis-Retinoic Acid Treatment of Steroid Acne
- The Effect of Oral Isotretinoin on the Barrier Function of the Lipsof Acne Patients and the Protective Role of Moisturizer
- A Case of Acne Fulminans Treated with Oral Isotretinoin and Systemic Corticosteroid
