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Recent Updates on Narcolepsy and Hypersomnia

Hong S

Narcolepsy is a chronic neurological sleep disorder caused by hypocretin neuron loss, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and intrusions of aspects of rapid eye movement sleep in...
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Obstructive Sleep Apnea in Women

Ayub S, Won CH

Obstructive sleep apnea is known to be more prevalent in men. In women the prevalence varies throughout her life span as she goes through different stages; puberty, reproductive years, pregnancy...
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Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity

Özcabı B, Demirhan S, Akyol M, Öztürkmen Akay H, Güven A

BACKGROUND: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. PURPOSE: Here we evaluated the ability of LAP to predict NAFLD...
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Pubertal outcomes and sex of rearing of patients with ovotesticular disorder of sex development and mixed gonadal dysgenesis

Kim YM, Oh A, Kim KS, Yoo HW, Choi JH

PURPOSE: Patients with ovotesticular disorder of sex development (DSD) and mixed gonadal dysgenesis (MGD) usually present with asymmetric gonads and have wide phenotypic variations in internal and external genitalia. The...
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Two Cases of Herlyn-Werner-Wunderlich Syndrome in Neonates and Adolescents with Hydrocolpos and Hematocolpometra

Park M, Jeon GH

The Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital anomaly that is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It is often diagnosed in patient...
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Relationship between Mothers' Diagnosis of Cervical Cancer and Attitudes toward Preventing Cervical Cancer in Their Pubertal Daughters

Lee DB, Kim HW

PURPOSE: This study was conducted to examine the relationship between a mother's diagnosis of cervical cancer and attitudes toward cervical cancer prevention in their daughters. Their intention to recommend human...
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Serum Procollagen Type I N-Terminal Propeptide and Osteocalcin Levels in Korean Children and Adolescents

Choi JS, Park I, Lee SJ, Ju HJ, Lee H, Kim J

PURPOSE: Bone markers can be useful for the diagnosis and treatment of skeletal diseases in children and adolescents. Owing to high skeletal growth velocity and rapid bone turnover, children and...
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Experiences of Precocious Puberty in Primary School Girls with Hormone Therapeutics

Cheon SM, Jung HY

PURPOSE: The purpose of this qualitative study was to identify the nature of precocious puberty and to explore what it means in primary schools. METHODS: The participants of this phenomenological study...
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Consequences of chemotherapeutic agents on primordial follicles and future clinical applications

Kim SY, Cho GJ, Davis JS

The ovarian reserve is necessary for female fertility and endocrine health. Commonly used cancer therapies diminish the ovarian reserve, thus, resulting in primary ovarian insufficiency, which clinically presents as infertility...
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Herlyn-Werner-Wunderlich Syndrome with Central Precocious Puberty: A Case Report

Han J, Lee JM, Kim GH, Kim SJ

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital anomaly of the genitourinary tract comprising uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. Patients with HWW syndrome usually present symptoms such as...
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Use of Topical Rapamycin as Maintenance Treatment after a Single Session of Fractionated COâ‚‚ Laser Ablation: A Method to Enhance Percutaneous Drug Delivery

Oh J, Kim J, Lee WJ, Lee JH

Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder with an incidence of approximately 1 in 5,000 to 10,000 live births. TSC has various clinical manifestations such as multiple...
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Basal serum luteinizing hormone value as the screening biomarker in female central precocious puberty

Heo S, Lee YS, Yu J

PURPOSE: Precocious puberty refers to the development of secondary sex characteristics before ages 8 and 9 years in girls and boys, respectively. Central precocious puberty (CPP) is caused by premature...
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Evaluation and management of amenorrhea related to congenital sex hormonal disorders

Yoon JY, Cheon CK

Primary amenorrhea is a symptom with a substantial list of underlying etiologies which presents in adolescence, although some conditions are diagnosed in childhood. Primary amenorrhea is defined as not having...
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Effect of melatonin on the onset of puberty in male juvenile rats

Venugopal

Melatonin or N-acetyl-5-methoxytryptamine, the fascinating molecule secreted by the pineal gland. Melatonin has a close interaction with hypothalamic-pituitary-gonadal axis. In non-seasonal breeders like rat its exact role in reproduction is...
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Methylphenidate and Central Precocious Puberty: A Probable Side Effect among Seven Children with the Attention Deficit Hyperactivity Disorder

Ergür AT, Gül H, Gül A

Methylphenidate (MPH) is the most preferred drug for treatment of the attention deficit hyperactivity disorder (ADHD). Here, we aimed to discuss the possible effects and mechanisms of MPH on precocious...
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Systematic Review on Sanitary Pads and Female Health

Woo J, Kim S, Kim H, Jeong KS, Kim E, Ha E

The majority of South Korean females use sanitary pads, which contain various organic solvents which could be excreted before and during their menstruation. However, they are not provided with findings...
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Pituitary magnetic resonance imaging abnormalities in young female patients with hypogonadotropic hypogonadism

Kang JY, Kim SH, Kim H, Ki H, Lee MH

OBJECTIVE: To elucidate the association between clinical and laboratory characteristics and pituitary magnetic resonance imaging (MRI) abnormalities in young female patients with hypogonadotropic hypogonadism (HH). METHODS: We retrospectively investigated a series...
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Thyroid function in girls with central precocious puberty

Jung G, Oh SB, Lee WY, Kim HR, Nam HK, Kim JH, Rhie YJ, Lee KH

PURPOSE: Obesity is a well-known risk factor for central precocious puberty (CPP). Recently, elevated thyroid stimulating hormone (TSH) was reported in obese youth. However, few data regarding the relationship between...
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Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy

Kim MS, Koh HJ, Lee GY, Kang DH, Kim SY

PURPOSE: This study aimed to investigate the outcomes of gonadotropin-releasing hormone agonist (GnRHa) therapy with or without growth hormone (GH) therapy for girls with idiopathic central precocious puberty (CPP). METHODS: The...
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Early-life exposure to endocrine-disrupting chemicals and pubertal development in girls

Lee JE, Jung HW, Lee YJ, Lee YA

Over the last decades, the onset of puberty in girls has occurred earlier, but the tempo of pubertal progression has been relatively slower, resulting in a younger age at puberty...
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