Ann Pediatr Endocrinol Metab.  2012 Mar;17(1):57-61. 10.6065/apem.2012.17.1.57.

A Boy with Adrenocortical Tumor Who Progressed to Central Precocious Puberty after Surgery

Affiliations
  • 1Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea. pedendo@dau.ac.kr
  • 2Department of Surgical Pathology, Dong-A University College of Medicine, Busan, Korea.
  • 3Department of Urology, Dong-A University College of Medicine, Busan, Korea.

Abstract

Adrenocortical tumors in children are rare and show various clinical symptoms. We present an 8-year-old boy with peripheral precocious puberty caused by adrenocortical tumor. He showed elevated serum DHEA-S and 17-hydroxyprogesterone, and computed tomography revealed an abdominal mass. After surgical resection, he developed central precocious puberty. We report a rare case that showed progression from peripheral precocious puberty to central precocious puberty.

Keyword

Adrenal cortex neoplasms; Child; Puberty, precocious

MeSH Terms

17-alpha-Hydroxyprogesterone
Adrenal Cortex Neoplasms
Child
Humans
Puberty, Precocious
17-alpha-Hydroxyprogesterone
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