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Genetic etiologies of central precocious puberty

Lee HS

Pubertal onset is a complex process, which is influenced by genetic and environmental factors, such as obesity and endocrine-disrupting chemicals. In addition, the timing of normal puberty varies between individuals...
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Gamma-Knife Radiosurgery for Hypothalamic Hamartoma-Related Epilepsy

Song JY, Lee JI, Shin HJ, Lee J, Lee J

Purpose: Hypothalamic hamartoma (HH), a rare congenital disorder, can cause intractable epilepsy and requires optimal surgical treatment. This study analyzed the clinical characteristics of HH and evaluated seizure outcomes and...
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The Influence of Maturity Fears and Appearance Interest on Self-concept among Lower-grade Elementary School Girls with Precocious Puberty

Nam HJ, Choi MY

Purpose: This study explored the relationships of maturity fears and appearance interest(interest in appearance, interest in weight) with self-concept among girls with precocious puberty. Methods: The participants for this study...
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Mothers’ Experiences of Caring for Children with Precocious Puberty: A Q-Methodological Approach

Lee HJ, You MA

Purpose: This study explored experiences of mothers caring for children with precocious puberty. Methods: Q-methodology was used for analyzing individual subjectivity. Seventy Q-statements were selected and scored by 50 participants...
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Serum Anti-Müllerian Hormone Levels in Precocious Puberty Girls according to Stage of GnRH Agonist Treatment

Nam HK, Kim HR, Rhie YJ, Lee KH

Few studies have investigated the long-term effects of gonadotropin-releasing hormone (GnRH) agonist treatment on the reproductive function of central precocious puberty (CPP) girls. In this cross-sectional study, we assessed the...
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The Diagnostic Value of Pelvic Ultrasound in Girls with Central Precocious Puberty

Lee SH, Joo EY, Lee JE, Jun YH, Kim MY

The gonadotropin-releasing hormone (GnRH) stimulation test is the gold standard for differentiating central precocious puberty (CPP) from exaggerated thelarche (ET). Because of this test's limitations, previous studies have clarified the...
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The Influence of Body Mass Index on Luteinizing Hormone Levels after Gonadotropin-Releasing Hormone Stimulation in Girls with Precocious and Advanced Puberty

Lee SY

PURPOSE: The aim of this study was to investigate the influence of body mass index (BMI) on the level of peak luteinizing hormone (LH) after gonadotropin-releasing hormone (GnRH) stimulation in...
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Sterile Abscess Formation Associated with Two Different Forms of Gonadotropin-Releasing Hormone Agonist in Central Precocious Puberty

Kim JM, Shin YL

Long-acting formulations of gonadotropin-releasing hormone (GnRH) agonists are indicated for treating central precocious puberty. Leuprolide acetate and triptorelin acetate are widely used in Korea. Local reactions related to GnRH agonists,...
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Growth Status and Body Composition in Children with Central Precocious Puberty and Early Puberty

Kim HJ, Kim YH, Chung S

PURPOSE: The aim of this study was to analyze the growth status and body composition in children with central precocious puberty (CPP ) and early puberty (EP). METHODS: One hundred and...
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Changes in the Predicted Adult Height after Gonadotropin-Releasing Hormone Agonist Treatment in Girls with Idiopathic True Precocious Puberty

Kwon EB, Lee SJ, Cha M, Kim SY

PURPOSE: We evaluated the effects of the timing of treatment initiation with gonadotropin-releasing hormone agonist (GnRHa) on the change in predicted adult height (PAH) in girls with idiopathic true precocious...
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Efficacy of a Single Luteinizing Hormone Measurement after GnRH Agonist Administration for Therapeutic Monitoring of Girls with Central Precocious Puberty

Kim YM, Choi JH, Lee BH, Yoo HW

PURPOSE: The effectiveness of gonadotropin releasing hormone (GnRH) agonist therapy in central precocious puberty (CPP) depends on the suppression of luteinizing hormone (LH) secretion. The purpose of this study was...
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Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome in a Child with Idiopathic Precocious Puberty

Kang B, Park SH, Kim DH, Lee BI, Kim MY, Lee JE

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare congenital disorder characterized by the congenital absence or hypoplasia of the uterus and the upper two thirds of the vagina due to mullerian duct...
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Factors Affecting Growth Velocity during Gonadotropin-Releasing Hormone Agonist Treatment in Girls with Idiopathic Central Precocious Puberty

Cho MS, Suh WS, Park SY, Choi YJ, Lee MH, Cho WK, Cho KS, Park SH, Hahn SH, Jung MH, Suh BK, Lee BC

PURPOSE: In some girls with central precocious puberty (CPP), growth velocity (GV) decreases below the age-appropriate normal range during gonadotropin-releasing hormone agonist (GnRHa) treatment. The purpose of this study was...
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A Boy with Adrenocortical Tumor Who Progressed to Central Precocious Puberty after Surgery

Chueh HW, Bak NR, Kim MJ, Yoo JH, Rho MS, Cho WY

Adrenocortical tumors in children are rare and show various clinical symptoms. We present an 8-year-old boy with peripheral precocious puberty caused by adrenocortical tumor. He showed elevated serum DHEA-S and...
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A Case of adrenocortical oncocytoma Presenting with Peripheral Precocious Puberty

Oh SH, Jung CW, Lee J, Lee BH, Kim DY, No DY, Yoo SH, Choi JH, Yoo HW

Adrenocortical oncocytoma is a rare adrenal gland tumor, and in most cases, benign and non-functioning. Functional adrenocortical oncocytoma has only been reported in eleven cases worldwide, including three children. These...
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Evaluation of Information of Websites on Precocious Puberty

Kim BK, Park SH, Sung HU, Park SY, Kwon YS, Jun YH, Kim SK, Lee JE

PURPOSE: To evaluate the quality and scientific accuracy of internet information regarding precocious puberty. METHODS: We identified websites by entering "precocious puberty" or "early puberty" into 5 search engines from May...
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The Relationship between Initial Body Mass Index and Body Mass Index after One Year of Gonadotropin-Releasing Hormone Agonist Therapy in Idiopathic True Precocious Puberty Girls

Yoon JY, Kang MJ, Kim SY, Seo JY, Yang SW, Lee YA, Lee JE, Chung HR, Shin CH

PURPOSE: The aim of this study is to evaluate the relationship between initial body mass index (BMI) and BMI after gonadotropin-releasing hormone agonist (GnRHa) treatment in idiopathic true precocious puberty...
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Effect of GnRH Analogs Leuprolide-Acetate and Triptorelin on Bone Mineral Density in Girls with Central Precocious Puberty

Bauer S, Nam HK, Rhie YJ, Park SH, Lee KH

  • KMID: 2384068
  • J Korean Soc Pediatr Endocrinol.
  • 2011 Aug;16(2):106-111.
PURPOSE: The objective of this study was to evaluate the effect of gonadotropin releasing hormone analog (GnRHa) treatment on bone mineral density (BMD) in girls with central precocious puberty (CPP)....
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Clinical Course of Childhood Onset Pseudoprecocious Puberty due to Autonomous Ovarian Cyst

Kim MJ, Jung HJ, Choi IJ, Hong SY

  • KMID: 2384065
  • J Korean Soc Pediatr Endocrinol.
  • 2011 Aug;16(2):86-91.
PURPOSE: There are few reports about the natural history of patients with pseudoprecocious puberty due to autonomous ovarian cyst. We reviewed the clinical course of 7 patients who had autonomous...
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Serum IGF-1 and IGFBP-3 Levels in Central Precocious Puberty Girls Treated with Gonadotropin Releasing Hormone Agonist (GnRHa)

Yi KH

PURPOSE: The purpose of this test was to investigate the changes of serum IGF-1 and IGFBP-3 levels during a one-year gonadotropin releasing hormone agonist (GnRHa) treatment in central precocious puberty...
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