Korean J Hepatobiliary Pancreat Surg.
2004 Sep;8(3):195-197.
Malignant Extragastrointestinal Stromal Tumor of the Gallbladder
- Affiliations
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- 1Department of Surgery, Chonbuk National University College of Medicine, Chonju, Korea. chobh@chonbuk.ac.kr
- 2Department of Pathology, Chonbuk National University College of Medicine, Chonju, Korea.
- 3Department of Internal Medicine, Chonbuk National University College of Medicine, Chonju, Korea.
Abstract
- The demonstration of CD 117 (KIT) expression in extragastrointestinal lesions has helped to validate extra-gastrointestinal stromal tumors. We report here on an exceedingly rare case of a malignant extragastrointestinal stromal tumor of the gallbladder. A 68-year-old male patient presented with a palpable and nontender mass occupying the entire right upper quadrant of his abdomen. The patient underwent open cholecystectomy. On gross examination, a firm, polypoid, 10x6 cm tumor protruded from the lumen of the gallbladder. Histologically, there were 88 mitotic figures per 10 high-power fields. The tumor cells were immunoreactive for CD 117, vimentin and CD 34. Immunostaining for CD 117 showed a dot-like staining pattern in about 20% of the tumor cell. The present case was an exceedingly rare entity occurring in the gallbladder, Currently, the patient is under follow-up for 6 months with no abnormal findings such as recurrence.
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