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Histopathological changes in gall bladder mucosa in relation to the number, and size of gallstones, and analysis of the findings in the context of age distribution of the patients: A perspective

Sharma S, Walia BS, Randhawa M, Sharma A, Dugg P, Pannu JS

Backgrounds/Aims: To study histopathological changes in gall bladder mucosa in cholelithiasis patients, and analyse their relation to the number and size of gallstones. These findings were evaluated in the context...
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The link between Helicobacter pylori infection and gallbladder and biliary tract diseases: A review

Lim KPK, Loong Lee AJ, Jiang X, Jie Teng TZ, Shelat VG

Helicobacter pylori is a gram-negative pathogen commonly associated with peptic ulcer disease and gastric cancer. H. pylori infection has also been reported in cholelithiasis, cholecystitis, gallbladder polyps, and biliary...
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Recent Updates on Management and Follow-up of Gallbladder Polyps

Son JH

Gallbladder polyps are a common incidental finding. Although most of these are benign, differentiating non-neoplastic from neoplastic polyps is challenging. Trans-abdominal ultrasound is the primary imaging study for diagnosing and...
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Radical surgery for stage IV gallbladder cancers: Treatment strategies in patients with limited metastatic burden

Patkar S, Patel S, Kazi M, Goel M

Backgrounds/Aims: The present study looked at the role of radical surgery in gallbladder cancers (GBC) with limited metastatic disease. Methods: The retrospective observational study was conducted to screen the database from...
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Gallbladder Sarcomatoid Carcinoma Diagnosed after Surgery

Cho YH, Cha SW, Cho YD, Lee MY, Chu CW, Hong SS, Jin SY

Sarcomatoid carcinoma is rarely diagnosed as gallbladder cancer. Its aggressive nature, due to the characteristics of both sarcoma and carcinoma, results in a poor prognosis. We report a case of...
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The technique of laparoscopic and robotic extended cholecystectomy for gallbladder cancer

Kim KH, Thrastardottir TO, Choi SH

The application of minimally invasive surgery for gallbladder cancer (GBC) is yet controversial. This article discusses the techniques of laparoscopic and robotic extended cholecystectomy. A 69-year-old male diagnosed with cT1-2N0...
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Clinicopathologic significance of the delta-like ligand 4, vascular endothelial growth factor, and hypoxia-inducible factor-2α in gallbladder cancer

Park S, Kim J, Jang W, Kim KM, Jang KT

Background: Gallbladder cancer (GBC) is usually detected in advanced stages with a low 5-year survival rate. Delta-like ligand 4 (DLL4), vascular endothelial growth factor (VEGF), and hypoxia-inducible factor-2alpha (HIF2α) have...
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Survival after extended resections for gallbladder cancer

Bhatti ABH, Dar FS, Riyaz S, Khan NY, Qureshi NR, Khan NA

Backgrounds/Aims: Locally advanced gallbladder cancer (GBC) is associated with survival limited to a few months. Extended resections (ER) are occasionally performed in this group and outcomes remain inconclusive. This study...
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Gallbladder wall thickness adversely impacts the surgical outcome

Alotaibi AM

Backgrounds/Aims: To evaluate surgical outcomes of patients with gallbladder wall thickness (GBWT) > 5 mm. Methods: Patients who underwent cholecystectomy were classified into two groups according to their GBWT status (GBWT+...
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Endoscopic and Endosonographic Palliation for Triple Obstruction Caused by Recurrent Gallbladder Cancer: A Case Report

Kim YR, Oh CH, Yang MJ

Gallbladder cancer is the most common cause of hilar biliary obstruction; however, it rarely causes combined biliary, duodenal, and colon triple obstruction. In this case, the quality of life for...
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Incidence of bactibilia and related factors in patients who undergo cholecystectomy

Moon DK, Kang JS, Byun Y, Choi YJ, Lee HW, Jang JY, Lim CS

Purpose: In general, bile is normally sterile. However, there are reports bactibilia may occur in certain instances, though the causal factors are unclear. We analyzed possible preoperative predictors of bactibilia...
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Contrast-Enhanced CT and Ultrasonography Features of Intracholecystic Papillary Neoplasm with or without associated Invasive Carcinoma

Kim JH, Kim JH, Kang HJ, Bae JS

Objective: To assess the contrast-enhanced CT and ultrasonography (US) findings of intracholecystic papillary neoplasm (ICPN) and determine the imaging features predicting ICPN associated with invasive carcinoma (ICPN-IC). Materials and Methods: In...
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Gallbladder-associated hospital admission and cholecystectomy rates across Australia and Aotearoa New Zealand (2004–2019): Are we over-intervening?

Mollah T, Christie H, Chia M, Modak P, Joshi K, Soni T, Qin KR

Backgrounds/Aims: To investigate if the increase in the number of cholecystectomies is proportional to symptomatic gallbladder-associated hospital admissions in Australia and Aotearoa New Zealand (NZ). Methods: National healthcare registries were used...
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The feasibility of percutaneous transhepatic gallbladder aspiration for acute cholecystitis after self-expandable metallic stent placement for malignant biliary obstruction: a 10-year retrospective analysis in a single center

Ohno A, Fujimori N, Kaku T, Hijioka M, Kawabe K, Harada N, Nakamuta M, Oono T, Ogawa Y

Background/Aims: Patients with acute cholecystitis (AC) after metallic stent (MS) placement for malignant biliary obstruction (MBO) have a high surgical risk. We performed percutaneous transhepatic gallbladder aspiration (PTGBA) as the...
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Acute Acalculous Cholecystitis associated with Cystic Duct Cancer Diagnosed after Endoscopic Ultrasonography

Jun H, Choi EK, Hyun CL, Lee SH

We present an interesting case of acute acalculous cholecystitis which was diagnosed as cystic duct cancer after endoscopic ultrasonography (EUS). A 63-year-old man visited to an emergency room (ER) because...
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The Superiority of  68Ga‑FAPI‑04 over  18F‑FDG in a Case of Gallbladder Cancer

Guo C, Peng D, Liu Y, Chen L, Huang Z

A 56-year-old man presented with vague upper abdominal pain for more than 4 months. His abdominal ultrasound and MRI showed thickening of the neck and base of the gallbladder and nodule...
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Optimal indication for single-incision laparoscopic cholecystectomy in benign gallbladder diseases

Park MS

Laparoscopic cholecystectomy has become a basic procedure for cholecystectomy due to rapid recovery and cosmetic satisfaction after surgery, and it is currently the primary treatment for most benign gallbladder diseases....
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Incidence, mortality and survival of gallbladder, extrahepatic bile duct, and pancreatic cancer using Korea central cancer registry database: 1999-2019

Kang MJ, Yun EH, Jung KW, Park SJ

Backgrounds/Aims: In Korea, pancreatic cancer and “gallbladder and extrahepatic bile duct cancer” were ranked the 8th and 9th most frequent cancers in 2019 and the 4th and 6th most common...
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Insulin-Like Growth Factor-1 Receptor Targeted Fluorescent Imaging for Gallbladder Cancer in Orthotopic Mouse Models

Choi JH, Park JY

Background/Aims: Gallbladder cancer is fatal, but fluorescent imaging technology can facilitate timely diagnosis and improve patient outcomes. Fluorophore-conjugated insulin-like growth factor-1 receptor (IGF-1R) targeted antibodies were used to visualize gallbladder...
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Necrotizing Gallbladder Torsion Masking as Acalculous Cholecystitis: A Review of Two Cases Treated with Successful Laparoscopic Cholecystectomy

Jung HI

Gallbladder torsion is a rare disease and it is very difficult to diagnose preoperatively because the signs, symptoms, and image findings are very similar to the other cases of acute...
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