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Insulin-Like Growth Factor-1 Receptor Targeted Fluorescent Imaging for Gallbladder Cancer in Orthotopic Mouse Models

Choi JH, Park JY

Background/Aims: Gallbladder cancer is fatal, but fluorescent imaging technology can facilitate timely diagnosis and improve patient outcomes. Fluorophore-conjugated insulin-like growth factor-1 receptor (IGF-1R) targeted antibodies were used to visualize gallbladder...
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Necrotizing Gallbladder Torsion Masking as Acalculous Cholecystitis: A Review of Two Cases Treated with Successful Laparoscopic Cholecystectomy

Jung HI

Gallbladder torsion is a rare disease and it is very difficult to diagnose preoperatively because the signs, symptoms, and image findings are very similar to the other cases of acute...
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Optimal timing of percutaneous transhepatic gallbladder drainage and subsequent laparoscopic cholecystectomy according to the severity of acute cholecystitis

Lee JS, Lee SJ, Choi IS, Moon JI

Backgrounds/Aims: The optimal timing of percutaneous transhepatic gallbladder drainage (PTGBD) and subsequent laparoscopic cholecystectomy (LC) according to the severity of acute cholecystitis (AC) has not been established yet. Methods: This single-center,...
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Endoscopic Ultrasound-guided Drainage in Pancreatobiliary Diseases

Kim TH, Chon HK

EUS-guided drainage for gallbladder, bile duct, pancreatic duct, and peripancreatic fluid collection has been performed more frequently in the last decade. The development of dedicated stents and delivery systems for...
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Increased Risk of Cancer after Cholecystectomy: A Nationwide Cohort Study in Korea including 123,295 Patients

Choi YJ, Jin EH, Lim JH, Shin CM, Kim N, Han K, Lee DH

Background/aims: Contradictory findings on the association between cholecystectomy and cancer have been reported. We aimed to investigate the risk of all types of cancers or site-specific cancers in patients who...
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Feasibility of surgeon-performed percutaneous transhepatic gallbladder drainages in patients with acute cholecystitis

Shin MH, Choi NK

Purpose: This study aimed to evaluate the feasibility of surgeon-performed percutaneous transhepatic gallbladder drainage (PTGBD). Methods: Patients treated with PTGBD for acute cholecystitis (AC), performed by surgeons at Chosun University Hospital...
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Incidental gallbladder cancer: a retrospective clinical study of 40 cases

Altiok M, Özdemir HG, Kurt F, Gul MO, Gumus S

Purpose: Cholecystectomy is one of the most common surgeries today due to gallbladder diseases. The most prevalent malignancy of the biliary tract is gallbladder cancer. We aimed to discuss the...
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Validation of the association of the cystic duct fibrosis score with surgical difficulty in laparoscopic cholecystectomy

Moon HH, Jo JH, Choi YI, Shin DH

Background: The level of surgical difficulty in laparoscopic cholecystectomy might be predictable based on preoperative imaging and intraoperative findings indicative of cholecystitis severity. Several scales for laparoscopic cholecystectomy have been...
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Relationship between high bile juice amylase levels and chronic bacterial infections in patients with gallbladder cancer

Park YM, Seo HI, Kim S, Hong SB, Lee NK, Kim DU, Han SY, Lee SJ, Kim JR

Purpose: Pancreatic enzyme reflux into the biliary tract is associated with chronic inflammation and increased cellular proliferation in the biliary epithelium, leading to biliary carcinoma. We evaluated the relationship between...
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Upper Gastrointestinal Bleeding with Cholecystoduodenal Fistula

Seo MW

Cholecystoduodenal fistula, caused by gallbladder stone, trauma, peptic ulcer disease, and malignancy, is an uncommon cause of upper gastrointestinal hemorrhage. I report a case of cholecystoduodenal fistula with upper gastrointestinal...
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Reviewing the potential role of radiation therapy in gallbladder cancer: an update

Kumar D, Kiran NM, Khosla D

Gallbladder cancer is a highly malignant disease with a poor prognosis. It is the most common cancer of the biliary tract pathway. Although surgery remains the treatment of choice for...
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Curative intent radical cholecystectomy followed by hyperthermic intraperitoneal chemotherapy in ruptured intraductal papillary neoplasm of gallbladder with invasive carcinoma

Choi G, Jang S, Choi M, Yang S, Lee C, Kang CM

Gallbladder cancer has a poor prognosis, especially in peritoneal carcinomatosis related to perforation of the gallbladder followed by bile spillage. Previously, curative-intent treatment was not considered in carcinomatosis from cancer...
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The Diagnosis and Treatment of Acute Cholecystitis

Kim KH

Acute cholecystitis (AC), defined as inflammation of the gallbladder, is mainly caused by gallstones. Over 90% of AC results from obstruction of the cystic duct by stones or sludge, which...
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Complete Transection of the Cystic Duct and Artery after Blunt Trauma: A Case Report

Cho SH, Lim KH

Extrahepatic biliary tract and gallbladder injuries following blunt abdominal trauma are uncommon. Traumatic cystic duct transection is even rarer, which has frequently caused missed diagnosis and delayed treatment. An 18-year-old...
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Gallbladder paraganglioma with hemorrhage: A case report and literature review

Song SH, Cho CK, Park EK, Kim HJ, Hur YH, Koh YS, Lee YH

Gallbladder paraganglioma (GP) is a rare tumor, with only 12 cases reported in the literature to date. Due to its rarity, clinical information of GP is insufficient. We present a...
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Laparoscopic ‘D2 first’ approach for obscure gallbladders

Gadiyaram S, Nachiappan M

Laparoscopic cholecystectomy has a reported incidence of 4%–15% of conversion to an open procedure and one of the main reasons behind the conversion is a gallbladder (GB) wrapped with dense...
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Bi-segmentectomy versus wedge hepatic resection in extended cholecystectomy for T2 and T3 gallbladder cancer: A matched case-control study

Nag HH, Nekarakanti PK, Sachan A, Nabi P, Tyagi S

Backgrounds/Aims: Extended cholecystectomy (EC) is the mainstay of treatment in most patients with potentially curable gallbladder cancer (GBC). The optimum extent of hepatic resection in EC is debatable. Methods: This retrospective...
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Limits of serum carcinoembryonic antigen and carbohydrate antigen 19-9 as the diagnosis of gallbladder cancer

Kang JS, Hong SY, Han Y, Sohn HJ, Lee M, Kang YH, Kim HS, Kim H, Kwon W, Jang JY

Purpose: Although serum CEA and CA 19-9 have been widely utilized for the diagnosis of gallbladder cancer (GBC), few studies have examined the diagnostic performance of them. This study aimed...
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Endoscopic Transpapillary Gallbladder Drainage for Acute Cholecystitis using Two Gallbladder Stents (Dual Gallbladder Stenting)

Sobani ZA, Sánchez-Luna SA, Rustagi T

Background/Aims: Endoscopic transpapillary gallbladder drainage (ETPGBD) is gaining popularity for the management of acute cholecystitis (AC) in high-risk patients. However, the stents placed during the procedure are not immune to...
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Minimally Invasive Approach Using Digital Single-Operator Peroral Cholangioscopy-Guided Electrohydraulic Lithotripsy and Endoscopic Nasogallbladder Drainage for the Management of High-Grade Mirizzi Syndrome

Chon HK, Park C, Kim TH

Mirizzi syndrome is a rare complication of gallbladder disease that can be difficult to treat. In particular, endoscopic treatment often fails because of the inability to access or to capture...
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