Korean J Anesthesiol.  2012 May;62(5):429-434. 10.4097/kjae.2012.62.5.429.

Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery

• Choi SJ
• Kim MH
• Jeong HY
• Lee JJ

• KMID: 2243821
• DOI: http://doi.org/10.4097/kjae.2012.62.5.429

Abstract

BACKGROUND
Perioperative lidocaine infusion improves postoperative outcomes, mostly after abdominal and urologic surgeries. Knowledge of the effect of lidocaine on peripheral surgeries is limited. Presently, we investigated whether intraoperative lidocaine infusion reduced anesthetic consumption, duration of ileus, pain intensity, analgesic consumption and hospital stay after breast plastic surgeries.
METHODS
Sixty female patients, aged 20-60 years, enrolled in this prospective study were randomly and equally divided to two groups. One group (n = 30) received a 1.5 mg/kg bolus of lidocaine approximately 30 min before incision followed by continuous infusion of lidocaine (1.5 mg/kg/h) until skin closure (lidocaine group). The other group (n = 30) was untreated (control group). Balanced inhalation (sevoflurane) anesthesia and multimodal postoperative analgesia were standardized. End tidal sevoflurane concentration during surgery, time to the first flatus and defecation, visual analog pain scale (0-10), analgesic consumption and associated side effects at 24, 48, and 72 h after surgery, hospital stay, and patient's general satisfaction were assessed.
RESULTS
Compared to the control group, intraoperative lidocaine infusion reduced by 5% the amount of sevoflurane required at similar bispectral index (P = 0.014). However, there were no significant effects of lidocaine regarding the return of bowel function, postoperative pain intensity, analgesic sparing and side effects at all time points, hospital stay, and level of patient's satisfaction for pain control.
CONCLUSIONS
Low dose intraoperative lidocaine infusion offered no beneficial effects on return of bowel function, opioid sparing, pain intensity and hospital stay after various breast plastic surgeries.

Keyword

Analgesic consumption; Anesthetic consumption; Bowel function; Hospital stay; Intravenous lidocaine; Pain score

MeSH Terms

Aged
Analgesia
Anesthesia
Breast
Defecation
Female
Flatulence
Humans
Ileus
Inhalation
Length of Stay
Lidocaine
Methyl Ethers
Pain Measurement
Pain, Postoperative
Prospective Studies
Skin
Lidocaine
Methyl Ethers