Korean J Gastrointest Endosc.
2005 Sep;31(3):180-184.
A Case of Cap Polyposis Successfully Managed with Infliximab
- Affiliations
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- 1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. ytjeen@korea.ac.kr
- 2Institute of Digestive Disease and Nutrition, Korea University College of Medicine, Seoul, Korea.
- 3Department of Pathology, Korea University College of Medicine, Seoul, Korea.
Abstract
- Cap polyposis is a rare disorder characterized by bloody, mucoid diarrhea with rectosigmoid polyps covered by a cap of fibrinopurulent exudate. The etiology and pathogenesis of cap polyposis is unknown, and no specific treatment has been established. Drug therapies are usually unsuccessful. Patients with a solitary cap polyp respond well to endoscopic polypectomy, while patients with multiple polyps and concurrent anorectal pathology require surgical resection. However, rapid recurrence has been described after a limited surgical resection, and this necessitates panproctocolectomy. We report a case of a 58-year-old female diagnosed as cap polyposis on rectum with similar clinical and endoscopic features of pseudomenbranous colitis successfully treated with infliximab (murine chimeric monoclonal antibody to TNF-alpha).
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