Korean J Anesthesiol.  1994 Apr;27(4):356-362. 10.4097/kjae.1994.27.4.356.

The Effect of Continuous Intravenous Infusion of Propofol Combined with Thoracic Epidural Anesthesia in Thoracic Surgery

• Kim JU
• Lee HW
• Kim BY
• Lim HJ
• Chae BK
• Chang SH

• KMID: 2236960
• DOI: http://doi.org/10.4097/kjae.1994.27.4.356

Abstract

Combined anesthesia has been associated with less sedation, earlier ambulation, higher pulmonary flow rates, improved oxygenation, blunting of stress response and better pain control in the postoperative period than general anesthesia. Total intravenous anesthesia has many advantages compared with inhalation anesthesia, but also has several disadvantages such as hypertension, inappropriate anesthetic, delayed recovery and emergence delirium For improvement of this problems, the authors tried epidural anesthesia combined with continuous intravenous infusion of propofol which is a short acting intravenous anesthetic and has characteristics of rapid and clear-headed recovery. Fifty-three patients undergoing elective thoracic operation were randomly assigned to receive anesthesia with N2O-O2-enflurane (n=23), epidural anesthesia combined with N2O-O2-propofol infusion (3 mg/kg/hy; n=15), or epidural anesthesia combined with medical air-O2-propofol infusion (6 mg/kg/hy; n=15). We studied the hemodynamic changes and occurence of awareness and recovery time on those three groups. Although there were significant changes in the hemodynamics among the groups except CVP, but all values were within normal limit and there were no difference in the recovery time. We concluded that epidural anesthesia with medical air-O2-propofol infusion (6 mg/kg/hr) is acceptable altemative method for thoracic surgery.

Keyword

Total intravenous anesthesia; Propofol; Epidural anesthesia

MeSH Terms

Anesthesia
Anesthesia, Epidural*
Anesthesia, General
Anesthesia, Inhalation
Anesthesia, Intravenous
Delirium
Hemodynamics
Humans
Hypertension
Infusions, Intravenous*
Oxygen
Postoperative Period
Propofol*
Thoracic Surgery*
Walking
Oxygen
Propofol