Korean J Anesthesiol.  1998 Feb;34(2):359-364. 10.4097/kjae.1998.34.2.359.

The Comparison of Propofol and Sodium Nitroprusside in Induced Hypotension undergoing Endoscopic Sinus Surgery

• Cho SY
• Cheong MA
• Kim KH
• Kim DW
• Jun JH
• Suh JK
• Yoo HK

• KMID: 2236876
• DOI: http://doi.org/10.4097/kjae.1998.34.2.359

Abstract

BACKGROUND
The general anesthesia for endoscopic sinus surgery (ESS) is associated with increase in intraoperative bleeding, which can interfere with optimal visualization through the endoscope, so we compared the effectiveness of propofol as induced hypotensive agent with sodium nitroprusside (SNP) in ESS.
METHODS
Twenty patients undergoing ESS under general anesthesia were allogated randomly to recieve thiopental sodium induction with enflurane maintenance and induced hypotension by SNP (SNP group), or propofol induction and propofol maintenance (propofol group). The two groups were recieved nalbuphine, vecuronium, nitrous oxide and oxygen for anesthesia. The hypotensive effects, hemodynamic changes were evaluated with mean arterial pressure (MAP), heart rate (HR), hematocrit of preoperative, intraoperative and postoperative period and estimated blood loss (EBL).
RESULTS
Mean arterial pressure was significantly decreased during hypotensive anesthesia (p<0.05), but any other parameters (HR, EBL and hematocrit change) were not significantly different in two groups.
CONCLUSION
Propofol has an effectiveness of hypotensive agent as SNP; and make endoscopic sinus surgery technically easier and safer by improving endoscopic visualization of the surgical field with less blood loss.

Keyword

Anesthetics, intravenous: propofol; Anesthetic techniques: induced hypotension; Surgery: Endoscopic sinus surgery

MeSH Terms

Anesthesia
Anesthesia, General
Arterial Pressure
Endoscopes
Enflurane
Heart Rate
Hematocrit
Hemodynamics
Hemorrhage
Humans
Hypotension*
Nalbuphine
Nitroprusside*
Nitrous Oxide
Oxygen
Postoperative Period
Propofol*
Sodium*
Thiopental
Vecuronium Bromide
Enflurane
Nalbuphine
Nitroprusside
Nitrous Oxide
Oxygen
Propofol
Sodium
Thiopental
Vecuronium Bromide