Korean J Anesthesiol.  2002 Aug;43(2):174-178. 10.4097/kjae.2002.43.2.174.

The Comparison of Incidence of Postoperative Agitation in Children after Enflurane or Sevoflurane Inhalation Anesthesia

• An TH

• KMID: 2236760
• DOI: http://doi.org/10.4097/kjae.2002.43.2.174

Abstract

BACKGROUND: An agitated recovery may occur after inhalation anesthesia. The aim of the present study was to assess the recovery quality after inhalation anesthesia with enflurane or sevoflurane in children.
METHODS
Thirthy children aged 2 - 11 years (classified as ASA physical status 1) scheduled for elective surgery were randomly assigned to receive either enflurane (n = 14) or sevoflurane (n = 16). All children were premedicated with midazolam (0.05 mg/kg) and glycopyrrolate (0.004 mg/kg) an hour before induction. Thiopenthal sodium (5 mg/kg) and vecuronium bromide (0.1 mg/kg) were used for the induction of anesthesia, and it was maintained by inhalation of enflurane 2 vol% or sevoflurane 2 vol% in N2O/O2 50/50 via an endotracheal tube. Recovery was assessed by a "blinded" observer using a postanesthetic recovery score. Recovery characteristics and agitation characteristics on emergence were also compared with each other between the two groups.
RESULTS
There were no differences between groups in respect of age, weight, duration of inhalation gas exposure. Recovery was faster with sevoflurane anesthesia. Agitation occurred more frequently with sevoflurane than enflurane. Duration of agitation was also longer with sevoflurane than enflurane.
CONCLUSIONS
The recovery of consciousness from sevoflurane anesthesia was fast, but postoperative agitation was more common in sevoflurane anesthesia.

Keyword

Agitation; children; enflurane; recovery; sevoflurane

MeSH Terms

Anesthesia
Anesthesia, Inhalation*
Child*
Consciousness
Dihydroergotamine*
Enflurane*
Glycopyrrolate
Humans
Incidence*
Inhalation*
Midazolam
Sodium
Vecuronium Bromide
Dihydroergotamine
Enflurane
Glycopyrrolate
Midazolam
Sodium
Vecuronium Bromide